An important function of the two-channel system for recording post-operative complications at Wrightington (Chap. 2) is the monitoring of various forms of prophylaxis against thrombo-em-bolism (TE). More than 1000 arthroplasties are performed each year at Wrightington, in reasonably controlled circumstances, so that the situation is very favourable for establishing clinical trials of different prophylactic agents.


Pulmonary Embolism Deep Venous Thrombosis Fatal Embolus Prophylactic Agent Fatal Pulmonary Embolism 
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  1. 43).
    Johnson, R., Green, J.A., Charnley, J. (1977): Pulmonary Embolism Following the Charnley Total Hip Replacement and its Prophylaxis. Clin. Orthop. 127, 123PubMedGoogle Scholar
  2. 44).
    Johnson, R., Charnley, J. (1977): Treatment of Pulmonary Embolism in Total Hip Replacement. Clin. Orthop. 124, 149PubMedGoogle Scholar
  3. 45).
    Johnson, R., Charnley, J. (1977): Hydroxychloroquine in Prophylaxis of Pulmonary Embolism Following Hip Arthroplasty. Internal Publication No. 74, Centre for Hip Surgery, Wrightington HospitalGoogle Scholar
  4. 46).
    Crawford, W.J., Hillman, F., Charnley, J. (1968): A Clinical Trial of Prophylactic Anticoagulant Therapy in Elective Hip Surgery. Internal Publication No. 14, Centre for Hip Surgery, Wrightington HospitalGoogle Scholar
  5. 47).
    Sharnhoff, J.G., DeBlasio, G. (1970): Prevention of Fatal Post-operative Thromboembolism by Heparin Prophylaxis. Lancet 2, 1006CrossRefGoogle Scholar
  6. 48).
    Charnley, J. (1972): Letter to Lancet Vol. 2, p. 134.CrossRefGoogle Scholar
  7. 49).
    Harris, W.H., Salzman, E.W., Athanasoulis, C., Waltman, A.C., Baum, S., De Saudis, R.W. (1974): Comparison of Warfarin, Low-Molecular-Weight Dextran, Aspirin and Subcutaneous Heparin in Prevention of Venous Thromboembolism following Total Hip Replacement. J. Bone Joint Surg. 56A, 1552Google Scholar
  8. 50).
    Carter, A.E., Eban, R. (1974): Prevention of Postoperative Deep Venous Thrombosis in Legs by Orally Administered Hydroxychloroquine Sulphate. Br. Med. J. 3, 94PubMedCrossRefGoogle Scholar
  9. 51).
    Chrisman, O.D., Snook, G.A., Wilson, T.C., Short, J.Y. (1976): Prevention of Venous Thrombosis by Administration of Hydroxychloroquine. J. Bone Joint Surg. 58A, 918Google Scholar
  10. 52).
    Jennings, J.J., Harris, W.R., Sarmiento, A. (1976): A Clinical Evaluation of Aspirin Prophylaxis of Thromboembolic Disease after Total Hip Replacement. J. Bone Joint Surg. 58A, 926Google Scholar
  11. 53).
    Coventry, M.B., Nolan, D.R., Beckenbaugh, R.D. (1973): “Delayed” Prophylactic Anticoagulants: A Study of Results and Complications in 2012 Total Hip Arthroplasties. J. Bone Joint Surg. 55A, 1487Google Scholar
  12. 54).
    Stamatakis, J.D., Kakkar, V.V., Lawrence, D., Bentley, P.G., Nairn, D., Ward, V. (1978): Failure of Aspirin to Prevent Post-operative Deep Vein Thrombosis in Patients Undergoing Total Hip Replacement. Br. Med. J. 1, 1031PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • John Charnley
    • 1
    • 2
    • 3
  1. 1.University of ManchesterUK
  2. 2.Centre for Hip SurgeryWrightington HospitalWigan, LancashireEngland
  3. 3.King Edward VII HospitalMidhurst, SussexUK

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