Feedback and Facilitation in the Adrenocortical System and the Endocrine Responses to Repeated Stimuli

  • M. F. Dallman
  • Ch. W. Wilkinson
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


In this paper we limit ourselves to discussion of stress-inducing stimuli and adrenocortical responses to stress in mammals. Emphasis is placed on the modification of these responses by feedback inhibition of glucocorticoids on (CRF and) ACTH secretion and by stress-induced facilitation in the adrenocortical system. Finally we discuss the effects of repeated activation of this system on the responses of other endocrine systems.


Endocrine Response Corticosterone Level Repeated Stimulus ACTH Secretion Plasma Corticosterone Level 
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© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • M. F. Dallman
  • Ch. W. Wilkinson

There are no affiliations available

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