The Concept of Capacity Limited Elimination of 4-Hydroxybutyrate

  • E. van der Kleijn
  • T. B. Vree
  • W. van der Pol
  • R. Deeleman
Part of the Anaesthesiologie und Intensivmedizin/Anaesthesiology and Intensive Care Medicine book series (A+I, volume 110)


In the course of studies of 4-hydroxybutyrate (Gamma-OH, Somsanit, 4-HB) in the dog (1) it became evident that this drug shows a rare pharmacokinetic profile.


Compartment Model Zero Order Kinetic Enzyme Capacity Apparent Distribution Volume Diphenyl Hydantoin Plasma Level 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • E. van der Kleijn
  • T. B. Vree
  • W. van der Pol
  • R. Deeleman

There are no affiliations available

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