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The Effect of Middle Cardiac Nerve Stimulation Upon the Respiratory Response to \({\operatorname{Pa} _{{{\operatorname{CO} }_2}}}\) in the Chicken

  • J. A. Estavillo
  • M. L. Youther
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Summary

Respiratory movements in 13 thoracotomized cockerels were recorded. The pulmonary circulation of the right lung was blocked, and the left perfused lung was denervated in order to determine the effects on respiratory movements of intrapulmonary CO2 tension,\({\operatorname{P} _{{{\operatorname{iCO} }_2}}}\), arterial CO2 tension (\({\operatorname{P} _{{{\operatorname{aCO} }_2}}}\)) and electrical stimulation of the left middle carciac nerve. At low \({\operatorname{P} _{{{\operatorname{iCO} }_2}}}\) respiratory movements changed little with varying \({\operatorname{P} _{{{\operatorname{aCO} }_2}}}\) ; conversely, at low \({\operatorname{P} _{{{\operatorname{aCO} }_2}}}\) respiratory movements changed little with varying \({\operatorname{P} _{{{\operatorname{aCO} }_2}}}\) . At 70-torr \({\operatorname{P} _{{{\operatorname{aCO} }_2}}}\), respiratory movements were maximal at \({\operatorname{P} _{{{\operatorname{iCO} }_2}}}\) of 33 torr or higher. Stimulation of the middle cardiac nerve (MCN) produced a reduction in respiratory movements at most levels but showed greater sensitivity at low intrapulmonary \({\operatorname{P} _{{{\operatorname{iCO} }_2}}}\) and \({\operatorname{P} _{{{\operatorname{aCO} }_2}}}\) levels. Receptors with axons in the MCN may be important in the control of avian respiration.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • J. A. Estavillo
    • 1
  • M. L. Youther
    • 1
  1. 1.Department of Basic Medical Education, School of MedicineSouthern Illinois UniversityCarbondaleUSA

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