Effect of Extirpation of the Cervical Sympathetic Ganglia on Development of the Neurosecretory Peptidergic and Parvocellular Nuclei of Rat Hypothalamus During Postnatal Ontogenesis

  • L. M. Lepekhina
Conference paper


Extirpation of the cervical sympathetic ganglia (CSG) results in retardation of the growth of young rats (EAYRS and TAYLOR, 1951; LEPEKHINA, 1975). Our purpose was to show the hypothalamic nuclei (supraoptic — SO, paraventricular — PV, suprachiasmatic — SCH, ventromedial — VM, dorsomedial — DM, arcuate — ARC) in which morphologic changes occur after extirpation of CSG in young rats, and to show how these changes are correlated with growth retardation. Twenty intact and twenty-six operated animals were studied during the course of 5 months of postnatal ontogenesis. A karyo- and cytometric study was made on the 10th, 20th, and 30th days after birth as well as at the ages of 2, 3, and 5 months. The results were treated statistically on the computer. Bilateral extirpation of the CSG was made within the first 5 days after birth.


  1. Eayrs, J.T., Taylor, S.H.: J. Anat. (Lond.) 85, 330–337 (1951)Google Scholar
  2. Lepekhina, L.M.: Bull. Exp. Biol. & Med. 79, 498–500 (1975) (in Russian)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • L. M. Lepekhina
    • 1
  1. 1.Sechenov Institute of Evolutionary Physiology and BiochemistryAcademy of Sciences of the USSRLeningradUSSR

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