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Porphyria Caused by Hexachlorobenzene and Other Polyhalogenated Aromatic Hydrocarbons

  • G. H. Elder
Chapter
Part of the Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology book series (HEP, volume 44)

Abstract

The polyhalogenated aromatic hydrocarbons which cause the specific form of hepatic porphyria described in this Chapter are shown in Figure 1. Prolonged administration of these compounds to susceptible mammals and birds leads to the development, after a delay which varies between species but is usually at least a week, of massive overproduction of uroporphyrin and heptacarboxyhc porphyrin and, to a lesser extent, porphyrins with 6, 5 and 4 carboxyl groups.

Keywords

Iron Overload Japanese Quail Smooth Endoplasmic Reticulum Porphyria Cutanea Tarda Hepatic Porphyria 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1978

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  • G. H. Elder

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