Cerebral Atherosclerosis: Morphology and Some Relationships with Coronary Atherosclerosis

  • J. Moossy


At the conclusion of a comprehensive review of the pathology of cerebral arteriosclerosis McMillan wrote: “Lastly, the similarities of cerebral arteriosclerosis with arteriosclerosis in other vascular beds are so numerous and its differences are so few that it should be considered the same pathological process for most purposes” (9). The statement remains valid and therefore raises the question of why we are contrasting and comparing cerebral and coronary atherosclerosis (arteriosclerosis) in this symposium. The histopathological, cytopathological and biochemical characteristics are with minor exceptions and variations the same in the various types of atherosclerotic lesions in all arterial systems (2, 5, 6, 8). Do comparisons of any type yield information of predictive or prognostic value for individuals or populations? There appear to be obvious but complex clinical relationships in certain populations. The frequency with which coronary heart disease (CHD) precedes and coesxists with cerebrovascular disease (CVD) and the fact that CHD is a significant cause of death in patients with CVD are but two of the more prominent clinical features linking the two disorders.


Vertebral Artery Atherosclerotic Lesion Coronary Atherosclerosis Intracranial Artery Fatty Streak 
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© Springer-Verlag Berlin Heidelberg 1977

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  • J. Moossy

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