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Distribution of Cerebral Blood Flow at Rest and During Mental Activation in Normals and in Patients with Brain Disorders

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Abstract

The cerebral blood flow is normally controlled by the oxidative metabolism of the nervous tissue (“metabolic regulation of CBF”) (12). Hence, measurements of the regional cerebral blood flow (rCBF) mirror regional functional changes in the brain. By means of multidetector devices and isotope techniques based upon residue detection (16), functional landscapes’ in the brain (8) or cerebral ‘ideograms’ (7) can be recorded at rest and during different forms of sensory-motor and mental activity.

The author was supported by the Swedish Medical Research Council (project No. B75-14X-00084-12A), by the Wallenberg and the Thuring Foundations in Stockholm.

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References

  1. BRUN, A., GUSTAFSON, L., INGVAR, D.H.: Clinical symptoms, neuropathological findings and regional cerebral blood flow in Alzheimer’s disease. Acta neurol scand. Submitted for publication. 1976.

    Google Scholar 

  2. FRANZEN, G., INGVAR, D.H.: Abnormal distribution of cerebral activity in chronic schizophrenia. J. Psychiat. Res. 12, 199–214 (1975).

    Article  PubMed  CAS  Google Scholar 

  3. FRANZEN, G., INGVAR, D.H.: Absence of activation in frontal structures during psychological testing of chronic schizophrenics. J. Neurol. Neurosurg. Psychiat..38., no. 10, 1027–1032 (1975).

    Article  PubMed  CAS  Google Scholar 

  4. HOUGAARD, K., OIKAWA, T., SVEINSDOTTIR, E., SKINHOJ, E., INGVAR, D.H., LASSEN, N.A.: Regional cerebral blood flow in focal cortical epilepsy. Arch. Neurol. Vol. 33, pp. 527–535, 1976.

    PubMed  CAS  Google Scholar 

  5. INGVAR, D.H.: rCBF in focal cortical epilepsy. In: Cerebral Circulation and Metabolism (LANGFITT,. LAWRENCE, MCHENRY,. REIVICH,. WOLFMAN, Eds.). Berlin-Heidelberg-New York: Springer 1975.

    Google Scholar 

  6. INGVAR, D.H.: Patterns of brain activity revealed by measurements of regional cerebral blood flow. In: Brain Work (D.H. INGVAR, N.A. LASSEN, Eds.), p. 397–413. Copenhagen: Munks-gaard 1975.

    Google Scholar 

  7. u, D.H.: The cerebral ideogram, L’Encephale, 1977, III, pp. 5–33.

    Google Scholar 

  8. INGVAR, D.H.: Functional landscapes of the dominant hemisphere. Brain Res. 107, 181–197 (1976).

    Article  PubMed  CAS  Google Scholar 

  9. INGVAR, D.H., FRANZEN, G.: Cerebral activity in chronic schizophrenia. Lancet 1974 II, 1484–1485.

    Article  Google Scholar 

  10. INGVAR, D.H., Gadea Ciria, M: Assessment of severe damage to the brain by multi-regional measurements of cerebral blood flow. In: A Ciba Symposium. Outcome of severe damage to the central nervous system p. 97–120. Amsterdam: Elsevier 1975.

    Google Scholar 

  11. INGVAR, D.H., HAGBERG, B.: Cognitive reduction in presenile dementia related to regional abnormalities of the cerebral blood flow. Brit. J. Psychiat, 128, 209–222 (1976).

    Article  PubMed  Google Scholar 

  12. INGVAR, D.H., LASSEN, N.A.: Brain Work. Kopenhagen: Munks-gaard 1975

    Google Scholar 

  13. INGVAR, D.H., PHILIPSON, L.: The concept of a hand movement and its cerebral ideogram. Ann. Neuro. 1977. In print.

    Google Scholar 

  14. INGVAR, D.H., ROSEN, I., ELMQVIST, D., ERIKSSON, M.: Activation patterns induced in the dominant hemisphere by skin stimulation. In: Sensory Functions of the Skin (Y. ZOTTERMAN, Ed.). London: Pergamon Press 1976.

    Google Scholar 

  15. INGVAR, D.H., SCHWARTZ, M.: Blood flow patterns induced in the dominant hemisphere by speech and reading. Brain 97, 273–288 (1974).

    Article  PubMed  CAS  Google Scholar 

  16. LASSEN, N.A., INGVAR, D.H.: Radioisotopic assessment of regional cerebral blood flow. In Progress in Nuclear Medicine, (J. POTCHEN et al., Eds.), p. 376–409. Basel-New York: Karger 1972.

    Google Scholar 

  17. LASSEN, N.A. et al.: Personal Communication, 1975.

    Google Scholar 

  18. LURIA, A.R.: Higher cortical functions in Man, London: Tavistock 1966.

    Google Scholar 

  19. OLESEN, J.: Contralateral focal increase of cerebral blood flow in man during arm work. Brain 94, 635–646 (1971),

    Article  PubMed  CAS  Google Scholar 

  20. PAULSON, O.B.: Cerebral apoplexy (stroke): Pathogenesis, patho-physiology and therapy as illustrated by regional blood flow measurements in the brain. Stroke 2, 327–360 (1971).

    Article  PubMed  CAS  Google Scholar 

  21. SKINNER, J.E., LINDSLEY, D.B.: The non-specific mediothalamic frontocortical system: its influence on electro-cortical activity and behaviour. In: Psychophysiology of the Frontal Lobes, (K.H. PRIBRAM, A.R. LURIA, Eds.) p. 185–234. New York: Academic Press 1973.

    Google Scholar 

  22. SVEINSDOTTIR, E., TORLöF, P., RISBERG, J., INGVAR, D.H., LASSEN, N.A.: Monitoring regional cerebral blood flow in normal man with a computer-controlled 32-detector system, Europ. Neurol. 6, 228–233 (1971/72).

    Article  PubMed  Google Scholar 

  23. SAPIRSTEIN, L.A., MELLETTE, H.: Use of antipyrine in regional blood flow measurements in the dog. Fed, Proc. 14, 129 (1955).

    Google Scholar 

  24. TER-POGOSSIAN, M.M., EICHLING, J.O., DAVIS, D.O., WELCH, M.J.: The measure in vivo of regional cerebral oxygen utilization by means of oxyhemoglobin labeled with radioactive oxagen -15. J. Clin, Invest. 49, 381–391 (1970).

    Article  CAS  Google Scholar 

  25. HOUGAARD, K., OIKAWA, T., SVEINSDOTTIR, E., SKINHOJ, E., INGVAR, D.H., LASSEN, N.A.: Regional cerebral blood flow in focal cortical epilepsy. Arch. Neurol. Vol. 33, pp. 527–535, 1976.

    PubMed  CAS  Google Scholar 

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Ingvar, D.H. (1977). Distribution of Cerebral Blood Flow at Rest and During Mental Activation in Normals and in Patients with Brain Disorders. In: Zülch, K.J., Kaufmann, W., Hossmann, KA., Hossmann, V. (eds) Brain and Heart Infarct. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66662-9_17

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  • DOI: https://doi.org/10.1007/978-3-642-66662-9_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66664-3

  • Online ISBN: 978-3-642-66662-9

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