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Density-dependent Growth Control and Lipid Mobilities in Normal and Tumor-Transformed Cell Membranes

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Structural and Kinetic Approach to Plasma Membrane Functions

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

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Abstract

Regardless of the inducing agent, transformed cells show membrane changes when compared to their normal counterparts. Transformed cells have been shown to possess, in many instances, enhanced lectin agglutinability (1–3), increased hexose transport across the membrane (4, 5), and, above all, the tendency to grow to very high densities in cell cultures (6). These observations generated the question of whether the physical properties of the plasma membrane of transformed cells would show any changes as compared to their normal counterparts and whether such changes might be correlated with the observed modifications in the membrane functions of the former.

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Authors
  1. C. Nicolau
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  2. K. Hildenbrand
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  3. A. Reimann
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  4. R. R. Friis
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  5. S. M. Johnson
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  6. A. Vaheri
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Editor information

Editors and Affiliations

  1. Institut für Strahlenchemie, Max-Planck Institut für Kohlenforschung, Mühlheim/Ruhr, Germany

    Claude Nicolau Ph. D. (Professor of Molecular Biology, Head of Laboratory, Visiting Professor) (Professor of Molecular Biology, Head of Laboratory, Visiting Professor)

  2. Texas Medical Center, Baylor College of Medicine, Houston, Texas, USA

    Claude Nicolau Ph. D. (Professor of Molecular Biology, Head of Laboratory, Visiting Professor) (Professor of Molecular Biology, Head of Laboratory, Visiting Professor)

  3. Station de Recherches de Virologie et d’Immunologie de l’INRA, Grignon, France

    Alain Paraf Dr. med. vet. (Directeur de Recherches Institut National de la Recherche Agronomique (INRA) (Directeur de Recherches Institut National de la Recherche Agronomique (INRA)

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© 1977 Springer-Verlag Berlin Heidelberg

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Nicolau, C., Hildenbrand, K., Reimann, A., Friis, R.R., Johnson, S.M., Vaheri, A. (1977). Density-dependent Growth Control and Lipid Mobilities in Normal and Tumor-Transformed Cell Membranes. In: Nicolau, C., Paraf, A. (eds) Structural and Kinetic Approach to Plasma Membrane Functions. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66659-9_9

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  • DOI: https://doi.org/10.1007/978-3-642-66659-9_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66661-2

  • Online ISBN: 978-3-642-66659-9

  • eBook Packages: Springer Book Archive

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