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Immunological Diagnosis of Leukemias and Lymphomas pp 307–313Cite as

The Significance of Chromosomal Findings for the Differentiation between Lymphoma and Lymphoblastoid Cell Lines

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Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 20))

Abstract

In lymphoid neoplasia, it has been difficult to distinguish between contaminating lymphoblastoid cells and truly malignant lymphoma cells. Certain cellular markers have been applied for this differentiation. Among these, cytogenetic findings like aneuploidy and marker chromosomes, as well as tumorgenicity in immunodeficient hosts have been proven to be the most valid parameters. This paper deals mainly with the role of cytogenetic markers.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Cologne, Germany

    K. P. Hellriegel, S. Meier & M. Blankenstein

  2. Division of Hematology, Department of Internal Medicine, Medizinische Hochschule Hannover, Germany

    V. Diehl

  3. Department of Pathology, Medizinische Hochschule Hannover, Germany

    P. H. Krause & W. Busche

Authors
  1. K. P. Hellriegel
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  2. V. Diehl
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  3. P. H. Krause
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  4. S. Meier
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  5. M. Blankenstein
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  6. W. Busche
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Editor information

Editors and Affiliations

  1. Institut für Hämatologie der Gesellschaft für Strahlen- und Umweltforschung, Landwehrstraße 61, D-8000, München 2, Bundesrepublik Deutschland

    Stefan Thierfelder , Hans Rodt  & Eckhard Thiel ,  & 

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© 1977 Springer-Verlag Berlin Heidelberg

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Hellriegel, K.P., Diehl, V., Krause, P.H., Meier, S., Blankenstein, M., Busche, W. (1977). The Significance of Chromosomal Findings for the Differentiation between Lymphoma and Lymphoblastoid Cell Lines. In: Thierfelder, S., Rodt, H., Thiel, E. (eds) Immunological Diagnosis of Leukemias and Lymphomas. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66639-1_38

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  • DOI: https://doi.org/10.1007/978-3-642-66639-1_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08216-3

  • Online ISBN: 978-3-642-66639-1

  • eBook Packages: Springer Book Archive

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