Chronic Lymphatic Leukemia Cells Bear IgM Receptors

  • W. J. Pichler
  • W. Knapp
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 20)


It is now generally accepted that the majority of chronic lymphatic leukemias (CLL) are malignant B cell proliferations. These leukemic B cells differ however in several respects from normal B cells; they frequently lack C3b receptors (1), the density of membrane immunoglobulins is lower in most cases of CLL than in normal B cells (2), they reveal a higher density of normal lymphoid membrane antigens (3), and they have an impaired proliferative response after antigenic or mitogenic stimuli (4).


Chronic Lymphocytic Leukaemia Helix Pomatia Chronic Lymphatic Leukemia Mediate Cytolysis Chronic Lymphatic Leukemia Cell 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1977

Authors and Affiliations

  • W. J. Pichler
    • 1
  • W. Knapp
    • 1
  1. 1.Institute for ImmunologyUniversity of ViennaAustria

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