Chronic Lymphatic Leukemia Cells Bear IgM Receptors

  • W. J. Pichler
  • W. Knapp
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 20)

Abstract

It is now generally accepted that the majority of chronic lymphatic leukemias (CLL) are malignant B cell proliferations. These leukemic B cells differ however in several respects from normal B cells; they frequently lack C3b receptors (1), the density of membrane immunoglobulins is lower in most cases of CLL than in normal B cells (2), they reveal a higher density of normal lymphoid membrane antigens (3), and they have an impaired proliferative response after antigenic or mitogenic stimuli (4).

Keywords

Lymphoma Leukemia Fractionation Trypsin Fluorescein 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1977

Authors and Affiliations

  • W. J. Pichler
    • 1
  • W. Knapp
    • 1
  1. 1.Institute for ImmunologyUniversity of ViennaAustria

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