The Polyunsaturated Fatty Acids in Human Platelets: Effects of Diet and Possible Functional Significance

  • R. Paoletti
Conference paper


A diet rich in saturated fats plus the addition of cholesterol, thiouracil, and cholic acid causes thrombosis in the rat (Thomas and Hartroft, 1959; Gresham and Howard, 1960; Renaud and Allard, 1962) and the thrombogenic effect of adenosine diphosphate is intensified by propylthiouracil added to a diet rich in saturated fats and cholesterol (Nordbøy and Chandler, 1964). A thrombogenic syndrome may be observed (Mustard et al., 1963) in pigs on a diet rich in saturated fats and cholesterol.


Arachidonic Acid Polyunsaturated Fatty Acid Cocoa Butter Erucic Acid Phosphatidic Acid 
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© Springer-Verlag Berlin Heidelberg 1977

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  • R. Paoletti

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