Summary
The spread of 14C sucrose through the brain was the same as the spread of Evan’s blue over the first 6 h after a cold injury to the cortex. The CSF level of sucrose was elevated (p < .001) from the 4th to the 24th h with a maximum at the 6th h. Autoradiographs showed the density of sucrose was greatest in the periventricular area at 6 h and that sucrose was completely cleared from the brain by 24 h. C14 dextran (75,000 mol wt) also showed significantly increased CSF levels 4–24 h after a cold injury with a maximum at 6 h. On autoradiography the dextran could be seen in the subarachnoid space and ventricles at 6 h. Dextran was still seen in the brain at 24 h.
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Bruce, D.A., Ter Weeme, C., Kaiser, G., Langfitt, T.W. (1976). The Dynamics of Small and Large Molecules in the Extracellular Space and Cerebrospinal Fluid Following Local Cold Injury of the Cortex. In: Pappius, H.M., Feindel, W. (eds) Dynamics of Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66524-0_21
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DOI: https://doi.org/10.1007/978-3-642-66524-0_21
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