Brain Edema and Blood Pressure Measurements in Unanesthetized Hypertensive Rats with Cortical Lesions

  • S. R. Nelson
  • A. R. Dick
  • R. D. Bunag
Conference paper


Seizures occurred after cold lesions were placed in spontaneously hypertensive rats but they did not occur in normotensive or DOCA hypertensive experimental rats. There were no changes in blood pressure or heart rate 2, 4, and 24 h after cryogenic lesions were made in normotensive and hypertensive rats. Edema was greater in some brain areas of hypertensive rats with cold lesions.


Middle Cerebral Artery Occlusion Brain Edema Tissue Volume Cortical Lesion Tygon Tubing 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1976

Authors and Affiliations

  • S. R. Nelson
    • 1
  • A. R. Dick
    • 1
  • R. D. Bunag
    • 1
  1. 1.Departments of Pharmacology and Neurology, Ralph L. Smith Research CenterKansas University Medical CenterKansas CityUSA

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