The Response of the Preimplantation Embryo to Exogenous Factors
The influence of exogenous agents upon the free-lying pre implantation embryo (blastocyst) is one of the areas of inquiry that is specifically concerned with the much wider problem of maternal-embryonic relationships and exchange reactions between the embryo and its environment. The mechanisms underlying these reactions are carefully adjusted by systems which act at the level of the endometrium and its secretory products, as well as those belonging to the blastocyst, and inherent in the zona pellucida, and the highly evolved trophoblastic elements. All these processes remain throughout under strict ovarian hormonal control; hormones emanating from the blastocysts themselves are probably also involved, as it has been shown that blastocysts contain several steroid hormones (Seamark and Lutwak-Mann, 1972) and a gonadotropin type of hormone (Haour and Saxena, 1974;Lutwak-Mann, unpublished).
KeywordsZona Pellucida Foreign Agent Preimplantation Embryo Exogenous Agent Embryonic Disk
Unable to display preview. Download preview PDF.
- Lutwak-Mann, C.: Experimental embryopathy as a tool in research on animal reproduction. In: Embryopathic Activity of Drugs. Biological Council Symposium, pp. 138–151. London: Churchill 1965.Google Scholar
- Lutwak-Mann, C.: Some physiological and biochemical properties of the mammalian blastocyst. Bull. Swiss Acad. med. Science 22, 101–122 (1966).Google Scholar
- Lutwak-Mann, C.: The rabbit blastocyst and its environment: physiological and biochemical aspects. In: The Biology of the Blastocyst, pp. 243–260. University of Chicago Press 1971.Google Scholar
- Lutwak-Mann, C.: Drugs and the blastocyst. In: Fetal Pharmacology, pp. 419–441. New York: Raven Press 1973.Google Scholar
- Lutwak-Mann, C., Hay, M.F.: Maternally transmissible embryotropic agents. In: Agents Affecting Fertility. Biological Council Symposium, pp. 261–274. London: Churchill 1965.Google Scholar
- Lutwak-Mann, C., Hay, M.F.: The blastocyst flat-mount technique in studies on embryotropic agents. In: Advances in Teratology, 1, pp. 229–238. London: Logos Press 1967.Google Scholar