Abstract
In 11 healthy test subjects and 8 patients with chronic arterial occlusive diseases, the blood flow properties were determined before and 15, 30 and 45 min. after the intravenous injection of 750 mg essential phospholipids (LIPOSTABIL, NATTERMANN). LIPOSTABIL did not change the “macro-rheological” parameters, such as hematocrit, blood viscosity and plasma viscosity. However, a statistically significant increase of the passage of erythrocytes did occur through a capillary filter (with capillaries of 8 um in diameter), which simulates the conditions prevailing in the microcirculation. In the patients with peripheral arterial occlusive diseases, an increase of the capillary filtrate could similarly be found, but these differences were just below the borderline of statistical significance. The present findings indicate that, in some way, the flow properties of the erythrocytes, and thus their deformability, are influenced in a manner such that their passage through narrow capillaries is facilitated, and the capillary flow-rate is thereby increased.
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Ehrly, A.M., Blendin, R. (1976). Influence of Essential Phospholipids on the Flow Properties of the Blood. In: Peeters, H. (eds) Phosphatidylcholine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66424-3_17
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DOI: https://doi.org/10.1007/978-3-642-66424-3_17
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