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The Inheritance of Maturity-Onset Type Diabetes in Young People

  • R. Tattersall

Abstract

In children, adolescents, and young adults two phenotypically distinct forms of diabetes can be recognized (Table 1). The classical and commoner form is characterized by an abrupt clinical onset, severe symptoms, lack of stimulated insulin output and a tendency to ketoacidosis (classical Juvenile-Onset Diabetes or JOD). The other form resembles typical maturity-onset diabetes of middle age in that symptoms at diagnosis are either mild or absent, stimulated insulin output is retained although delayed and diminished, there is no ketonuria and hyperglycemia can be controlled without insulin (Maturity-Onset type Diabetes of Young people or MODY). In practice there is inevitably some over lapping between these two arbitrary categories and the classification can only be made with certainty in retrospect (27).

Keywords

Young People Mild Diabetes Carbohydrate Intolerance Chemical Diabetes Diabetic Parent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1976

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  • R. Tattersall

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