Cell Division and DNA Replication in Synchronous Tetrahymena Cultures

  • H. A. Andersen
  • Leif Rasmussen
  • Erik Zeuthen
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 72)


Several methods are available for the induction of synchronous cell divisions in pro- and eukaryote cells. The present article deals almost exclusively with the synchronization of the ciliate protozoan Tetrahymena pyriformis, which is one of the cells most intensively studied in synchronous populations. As it will appear from the following pages Tetrahymena has been synchronized with several different procedures. The first of these was the multiple heat shock system which produced well-synchronized cell divisions. Later modification of the original programme synchronized not only cell division but also DNA replication. Since most of the work based on synchronized Tetrahymena cells has been done with heat-synchronized cells, recent results obtained with such cells will take up most of this review.


Heat Shock Cell Division Cell Generation Temperature Shock Cell BioI 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin · Heidelberg 1975

Authors and Affiliations

  • H. A. Andersen
    • 1
  • Leif Rasmussen
    • 1
  • Erik Zeuthen
    • 1
  1. 1.The Biological Institute of the Carlsberg FoundationCopenhagen NDenmark

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