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Investigations on the Metabolism and Protein Binding of Nifedipine

  • K. Schlossmann
  • H. Medenwald
  • H. Rosenkranz

Abstract

Studies in man, dog, and rat showed that nifedipine is almost completely absorbed [2, 3]. Excretion is mainly renal. The urine contains only traces of the unchanged substance, which means that nifedipine is transformed in the body and eliminated in metabolized form.

Keywords

Free Acid Main Metabolite Pyridine Derivative Coronary Sinus Blood Sodium Vapor Lamp 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    BOSSERT, F.: Vortragstagung der Gesellschaft Deutscher Chemiker, Fachgruppe Medizin, Bad Nauheim, Nov. 1972.Google Scholar
  2. 2.
    DUHM,B., MAUL,W., MEDENWALD, H., PATZSCHKE,K., WEGNER,L.: Arzneim.-Forsch. (Drug Res.) 22,42(1972).Google Scholar
  3. 3.
    HORSTER,F.A., DUHM,B., MAUL,W., MEDENWALD,H., PATZSCHKE, K., WEGNER,L.: Arzneim.- Forsch. (Drug Res.) 22, 330 (1972).Google Scholar
  4. 4.
    MEDENWALD,H., SCHLOSSMANN, K., WUNSCHE,C: Arzneim.-Forsch. (Drug Res.) 22, 53 (1972).Google Scholar
  5. 5.
    ROSENKRANZ, H., SCHLOSSMANN, K., SCHOLTAN,W.: Arzneim.-Forsch. (Drug Res.) 24,455 (1974).Google Scholar
  6. 6.
    SCHLOSSMANN,K.: Arzneim.-Forsch. (Drug Res.) 22,60 (1972).Google Scholar
  7. 7.
    SCHLOSSMANN, K., HARZDORF,C.: unpublished results (1972).Google Scholar
  8. 8.
    SCHOLTAN,W.: Arzneim.-Forsch. (Drug Res.) 15, 1433 (1965).Google Scholar
  9. 9.
    VATER,W., KRONEBERG,G., HOFFMEISTER,F., KALLER,H., MENG,K., OBERDORF,A., PULS, W., SCHLOSSMANN, K., STOEPEL,K.: Arzneim.-Forsch. (Drug Res.) 22,1 (1972).Google Scholar
  10. 10.
    VATER,W.: unpublished results (1974).Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1975

Authors and Affiliations

  • K. Schlossmann
    • 1
  • H. Medenwald
    • 1
  • H. Rosenkranz
    • 1
  1. 1.Forschungslaboratorien der Bayer AGLeverkusen und Wuppertal-1Fed. Rep. Germany

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