Investigations on the Metabolism and Protein Binding of Nifedipine

  • K. Schlossmann
  • H. Medenwald
  • H. Rosenkranz


Studies in man, dog, and rat showed that nifedipine is almost completely absorbed [2, 3]. Excretion is mainly renal. The urine contains only traces of the unchanged substance, which means that nifedipine is transformed in the body and eliminated in metabolized form.


Free Acid Main Metabolite Pyridine Derivative Coronary Sinus Blood Sodium Vapor Lamp 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1975

Authors and Affiliations

  • K. Schlossmann
    • 1
  • H. Medenwald
    • 1
  • H. Rosenkranz
    • 1
  1. 1.Forschungslaboratorien der Bayer AGLeverkusen und Wuppertal-1Fed. Rep. Germany

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