Abstract
Angina pectoris is one of the most distressing manifestations of ischemic heart disease, and its medical management is often difficult. One approach to its treatment has involved the use of vasodilator drugs, of which glyceryl trinitrate is the most commonly used [6]. Unfortunately, while acutely administered glyceryl trinitrate is undoubtedly efficacious, results with so-called “long-acting vasodilators” have been much less impressive [1, 5, 17].
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BATTOCK,D.J., ALVAREZ, H., CHIDSEY,C. A.: Effect of propranolol and isosorbide dinitrite on exercise performance and adrenergic activity in patients with angina pectoris. Circulation 39,157(1969).
BURKETT, D.A., CHAMBERLAIN,D.A.: Beta-adrenergic blockade in angina pectoris—a method of treadmill assessment. Brit. Med. J. 2,500 (1966).
EBNER,F.: Summary of results obtained during the world wide clinical investigations on Nifedipine. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
FLECKENSTEIN,A.: Adalat, a powerful Ca-antagonistic drug. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
GOLDBARG,A.N., MORAN,J.F., BUTTERFIELD,T.R., NEMICKAS,R., BERMUDEZ,G.A.: Therapy of angina pectoris with propranolol and long-acting nitrates. Circulation 40, 847 (1969).
GOLDSTEIN,R.E., EPSTEIN,S.E.: Mecidal management of patients with angina pectoris. Prog. Cardiovasc. Dis. 15,360 (1972).
GRUN,G.: Ca-dependent changes in coronary smooth muscle tone and the action of Caantagonistic compounds with special reference to Adalat. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
HAMER,J., SOWTON,E.: Effects of propranolol on exercise tolerance in angina pectoris. Amer. J. Cardiol. 18,354 (1966).
HORSTER,F.A.: Pharmacokinetical investigations with labelled Adalat in humans. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
KIRCHHEIM, H., GROSS,R.: Hemodynamic effects of Adalat in the unanesthetised dog. 2nd Intern. Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
LICHTLEN,P.: Coronary and left ventricular dynamics under Adalat, in comparison to nitrates, beta blocking agents and dipyridamole. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
LYDTIN,H., LOHMOLLER,G., LOHMOLLER,R., SCHMITZ,H., WALTHER,I.: Hemodynamic studies on Adalat in healthy volunteers and patients. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
MASON,D.T., BRAUNWALD,E.: The effects of nitroglycerin and amyl nitrite on arteriolar and venous tone in the human forearm. Circulation 32,755 (1965).
MCILWRAITH,G.: Antianginal efficacy of Adalat under loading conditions. 2nd International Adalat Symposium. Berlin-Heidelberg-New York: Springer 1975.
MURRAY,G., TWEDDEL,A., MCARTHUR,J.D., LAWRIE,T.D.V.: Unpublished observations.
REDWOOD,D.R., ROSING, D. R., GOLDSTEIN, R. E., BEISER,G.D., EPSTEIN, S. E.: Importance of the design of an exercise protocol in the evaluation of patients with angina pectoris. Circulation 43,618 (1971).
RUSSEK,H.I.: Therapeutic role of coronary vaso-dilators: glyceryl trinitrate isosorbide dinitrate and pentaerythritol tetranitrate. Amer. J. Med. Sci. 252,9 (1966).
SCHWARTZ,A.M.: The cause, relief and prevention of headaches arising from contact with dynamite. N ew Eng. J. Med. 235, 541 (1946).
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Mcarthur, J.D., Murray, R.G., Tweddel, A., Lawrie, T.D.V. (1975). Comparison of the Effect of Adalat and Propranolol on Exercise Tolerance in Patients with Angina Pectoris. In: Lochner, W., Braasch, W., Kroneberg, G. (eds) 2nd International Adalat® Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66241-6_41
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DOI: https://doi.org/10.1007/978-3-642-66241-6_41
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