Effects of Intracranial Hypertension, Low-Pressure Hydrocephalus and Subsequent Ventriculo-Peritoneal Shunting on Monoamine Neurons in Rabbit Brain

  • Christer Owman
  • Lars Edvinsson
  • Evald Rosengren
  • Niels Svendgaard
  • Kurt A. West
Conference paper


Intracranial hypertension and hydrocephalus may produce functional disturbances in the brain which, to a certain extent, are manifested in neurological symptoms. The damage to the brain parenchyma can also be estimated in terms of alterations in certain biochemical parameters, but it is difficult to distinguish to which extent such alterations are associated with the neurons or with other components of the brain. More specifically, the neuronal injury can be studied by morphological approaches, either at the level of optical or electron microscopy. However, it should be born in mind that a neuronal impairment which is demonstrable by morphological techniques, has already reached a fairly advanced stage.

Key words

Kaolin intracracranial hypertension brain monomines ventriculoperitoneal shunting 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1975

Authors and Affiliations

  • Christer Owman
  • Lars Edvinsson
  • Evald Rosengren
  • Niels Svendgaard
  • Kurt A. West

There are no affiliations available

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