CSF Resistance to Flow as an Aid to Diagnosis of Normal Pressure Hydrocephalus

  • Pierre Janny
  • Bernard Flori
  • Jean-Patrice Jouan
  • Laurent Janny
Conference paper


Pneumoencephalography (PEG) and isotope cisternography (IC) are sometimes unable to differentiate patients who will benefit from a shunt from those psychiatric patients who show enlarged ventricles and normal ICP. With the assumption that there exists an impairment of the CSF circulation in these patients, it would be interesting to examine whether the measurement of the CSF resistance to flow (Rf), as we have previously studied (1), would be an aid to this diagnosis.


Infusion test resistance to flow Alzheimer’ disease normal pressure hydrocephalus 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    JANNY, P., GODENECHE, P., FLORI, B., RAYNAUD, E.J.: La résistance à l’écoulement du liquide céphalo-rachidien. Méthode de mesure et application clinique. Rev. Neurol. 128, 161–170 (1973).PubMedGoogle Scholar
  2. 2.
    KATZMAN, R., HUSSEY, F.: A simple constant-infusion manometric test for measurement of CSF absorption. 1. Rationale and method. Neurology (Minneap.) 20, 534–544 (1970).Google Scholar
  3. 3.
    DAVSON, H., HOLLINGSWORTH, G., SEGAL, M.B.: The mechanism of drainage of cerebrospinal fluid. Brain 93, 665–678 (1970).PubMedCrossRefGoogle Scholar
  4. 4.
    NELSON, J.R., GOODMAN, S.J.: An evaluation of the cerebrospinal fluid infusion test for hydrocephalus. Neurology 21, 1037–1053 (1971).PubMedGoogle Scholar
  5. 5.
    WOLINSKY, J.S., BARNES, B.D., MARGOLIS, M.T.: Diagnostic tests in normal pressure hydrocephalus. Neurology 23, 706–713 (1973).PubMedGoogle Scholar
  6. 6.
    MARTINS, A.N.: Resistance to drainage of cerebrospinal fluid: clinical measurement and significance. J. Neurol. Neurosurg. Psychiat. 36, 313–318 (1973).PubMedCrossRefGoogle Scholar
  7. 7.
    COBLENZ, J.M., MATTIS, S., ZINGESSER, C.H., KASOFF, S.S., WISNIEWSKI, H.M., KATZMAN, R., BRONX, N.Y.: Presenile dementia — clinical aspects and evaluation of cerebrospinal fluid dynamics. Arch. Neurol. 29, 299–308 (1973).Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1975

Authors and Affiliations

  • Pierre Janny
  • Bernard Flori
  • Jean-Patrice Jouan
  • Laurent Janny

There are no affiliations available

Personalised recommendations