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Differences between Human and Animal Atherosclerosis

  • Robert W. Wissler
  • Dragoslava Vesselinovitch

Abstract

Atherosclerosis, perhaps more than any other widespread and life-threatening pathological process of modern times, needs to be studied using experimental models. It is very difficult to study the pathogenesis of this disease process adequately in man because it has a complex, multi-faceted set of initiating and augmenting factors; it comes on slowly over a long life span; and it produces essentially no clinical effects until it is far advanced. Furthermore, it is very difficult, short of relatively risky invasive techniques, to document the severity of atherosclerosis in any part of the arterial tree until it produces clinical effects (McGill et al., 1963).

Keywords

Thoracic Aorta Small Artery Fatty Streak Atherogenic Diet Serum Sickness 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1974

Authors and Affiliations

  • Robert W. Wissler
  • Dragoslava Vesselinovitch

There are no affiliations available

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