Effect of Ēthrane, Halothane and Penthrane on Alveolar Surfactants
the respiratory mechanism with reference to the curve for tension versus surface area. The stage of this curve at which the lungs become inflated depends on several factors, i. e. surface tension, initial pressure, and elasticity of the lungs. The curve obtained during deflation, in contrast, is an obvious indication of the strength due to surface tension. A statistical comparison of the values obtained from the deflation curve for transpulmonary pressure was made: these values reflected modifications in the strength of the alveolar surface.
The chemical composition of the alveolar surfactant was determined by washing the lung wi th a physiological solution that was cooled to 4°C and extracted by Folch’s method, before being analyzed by thin-layer chromatography.
The histological picture showed prominent histochemical pneumocytes Type II, and the cells that produce the alveolar surfactant were visualized by fixing and staining by the mixed Os-I-Method.