Vinca Alkaloids and Colchicine

  • William A. Creasey
Part of the Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology book series (HEP, volume 38 / 2)

Abstract

The vinca alkaloids and the colchicine derivatives, although of widely disparate chemical structure, may be considered to constitute a single class of agents in view of the many similarities in their biochemical and biological actions, most notably in their ability to produce metaphase arrest. This resemblance extends to certain other unrelated compounds, including griseofulvin and podophyllotoxin.

Keywords

Arthritis Leukemia Neuropathy Sarcoma Neurol 

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References

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© springer-Verlag Berlin-Heidelberg 1975

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  • William A. Creasey

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