Daunomycin (Daunorubicin) and Adriamycin

  • A. DiMarco
Part of the Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology book series (HEP, volume 38 / 2)


Daunomycin (NSC-82151) is an antibiotic isolated from cultures of Streptomyces peucetius (DiMarco et al., 1963, 1964a, b). While weakly active against some gram positive microorganisms, the drug inhibits the multiplication of coliphages more than that of the host bacteria (Sanfilippo et al., 1964) and exhibits marked cytotoxic activity against normal and neoplastic cells (DiMarco et al., 1964).


HeLa Cell Mitotic Index Rous Sarcoma Virus Nucleic Acid Synthesis Ehrlich Ascites Tumor 
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© Springer-Verlag Berlin-Heidelberg 1975

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  • A. DiMarco

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