Effect of Invertebrate Hormones and Oncogenic Viruses on Polytene Chromosomes

  • Walter J. Burdette
  • James E. CarverJr.


Recognition that the banded pattern observed in some cells represented prophase chromosomes in the larval salivary glands of Drosophila melanogaster by Painter (1933) and in the malpighian tubules of Bibio hortulanus L. independently by Heitz and Bauer (1933) first provided a means for visualizing the position of genes accurately and later for studying possible causes and effects of genie activation. The polytene nature of these prophase chromosomes proposed by Koltzoff (1934) was incorporated into the interpretation of their morphology; and through fortunate collaboration, Muller, Painter, Patterson, and others correlated the position and type of mutants produced by x-irradiation in Drosophila on crossover maps and salivary-gland chromosomes. Codification of this information into reliable chromosomal maps for different species of Drosophila by Bridges (1935) and later by others then provided means for visual interpretation of location and action of genes that has been invaluable over the years. Polytene chromosomes have been observed both in larval tissues that undergo dissolution with metamorphosis and tissues persisting in the imago. These include salivary glands, fat body, epidermal cells, muscle cells, various parts of the alimentary tract, neural cells, nuclei of trachea, imaginal discs, nurse cells of the ovary, vesiculae seminales, and malpighian tubules.


Salivary Gland Juvenile Hormone Polytene Chromosome Hormonal Control Malpighian Tubule 
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© Springer-Verlag New York Inc. 1974

Authors and Affiliations

  • Walter J. Burdette
  • James E. CarverJr.

There are no affiliations available

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