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The Influence of Ventilatory Changes on CSF Lactate and CSF L/P-Ratio in Brain Injury

  • R. Schubert
  • T. Wallenfang
  • H. J. Reulen
  • K. Schürmann
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 1)

Abstract

Diagnostic and prognostic evaluation of patients with severe head injury by means of measurable values in an urgent and not yet satisfactorily fulfilled clinical need. In recent years changes in CSF lactate and pyruvate concentrations in patients with head injury have been pointed out by various authors with the suggestion to apply them to clinical diagnosis and prognosis. Lactacidosis and increased lactate/pyruvate ratio in CSF have been demonstrated in the pressure of serious damage of brain tissue, e. g. in patients with severe head injuries. CROCKARD and TAILOR (1) observed a correlation between the amount of CSF lactacidosis and prognosis, indicating that patients whose CSF-pH decreased below a certain level did not recover.

Keywords

Head Injury Lactate Concentration Severe Head Injury Pyruvate Concentration Ventilatory Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    CROCKARD, H. A. and A. R. TAYLOR: Arterial CSF lactate/pyruvate values as a guide to prognosis in head injury coma. In: Cerebral Blood Flow and Intracranial Pressure. S. Karger, Basel (1972)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1973

Authors and Affiliations

  • R. Schubert
  • T. Wallenfang
  • H. J. Reulen
  • K. Schürmann

There are no affiliations available

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