Abstract
The task of reporting about hyperventilation in the sense of increased alveolar ventilation and its influence especially on the brain oedema seemed difficult from the neurosurgical point of view. There seem to be only few exact studies that are apt for clinical interpretation. For this reason, it seems necessary to accept the cerebrospinal fluid pressure (CSF pressure) as a further factor of intracranial pressure. In the course of a lumbar tapping, BARANY observed in 1912, that hyperventilation leads to a reduction in CSF pressure. After that it was especially LUNDBERG and co-workers (1959) who observed the ratio of ventricle fluid pressure (VFP) and the changes in the minute volume, for example, in the of a 60-year old patient having a temporal glioblastoma. The average VFP of 30 mmHg, corresponding to approx.. 40 mm H2O, was measured under spontaneous breathing of 5–6 1/min. Artificial increase of the minute volume for 1–2 hours to 15 and more 1/min. reduced the VFP to less than 275 mm H2O.
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Frowein, R.A., Karimi-Nejad, A., Richard, K.B. (1973). Influence of Ventilation and Hyperventilation on Brain Edema and Intracranial Pressure. In: Schürmann, K., Brock, M., Reulen, HJ., Voth, D. (eds) Brain Edema / Cerebello Pontine Angle Tumors. Advances in Neurosurgery, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65734-4_16
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