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Measurement of “Interstitial Fluid” Pressure in the Brain in Dogs

  • P. Brodersen
  • K. Højgaard
  • N. A. Lassen

Abstract

The interstitial fluid pressure is the hydrostatic pressure of the fluid between the solid tissue elements such as cells, fibers and vessels. Guyton measured negative pressures in chronically implanted perforated capsules, which he considered to be the true interstitial pressure in the subcutis [1], Others showed that a cotton wick inserted in a needle or catheter recorded a negative pressure in the subcutis within a few minutes just as the Guyton capsule did [2, 3].

Keywords

Negative Pressure Fluid Pressure Brain Edema Interstitial Fluid Interstitial Fluid Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Guyton, A. C.: A concept of negative interstitial pressure based on pressures in implanted perforated capsules. Circulat. Res. 12, 399–414 (1963).Google Scholar
  2. 2.
    Scholander, P. F., Hargens, A. R., Miller, S. L.: Negative pressures in the interstitial fluid of animals. Science 161, 321–328 (1968).PubMedCrossRefGoogle Scholar
  3. 3.
    Ladegaard-Pedersen, H. J.: Measurement of the interstitial pressure in subcutaneous tissue in dogs. Circulat. Res. 26, 765–770 (1970).Google Scholar
  4. 4.
    Brock, M., Winkelmüller, W., Pöll, W., Markakis, E., Dietz, H.: Measurement of brain-tissue pressure. Lancet I, 595–596 (1972).CrossRefGoogle Scholar
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    Guyton, A. C., Granger, H. J., Taylor, A. E.: Interstitial fluid pressure. Physiol. Rev. 51, 527–563 (1971).PubMedGoogle Scholar
  6. 6.
    Stromberg, D. G., Wiederhielm, C. A.: Effects of oncotic gradients and enzymes on negative pressure in implanted capsules. Amer. J. Physiol. 219, 928–932 (1970).PubMedGoogle Scholar
  7. 7.
    Kirsch, K., Rafflenbeul, W., Roedel, H.: Untersuchungen zur Ursache des negativen interstitiellen Gewebsdruckes (Guytonkapsel). Pflügers Arch. ges. Physiol. 328, 193–204 (1971).CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin 1972

Authors and Affiliations

  • P. Brodersen
  • K. Højgaard
  • N. A. Lassen

There are no affiliations available

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