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Bioenergetics and Properties and Function of Proteins in Excitable Membranes Associated with Bioelectrogenesis

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Molecular Bioenergetics and Macromolecular Biochemistry

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Abstract

Professor H. H. Weber has outlined in his lecture some of the fundamental notions and concepts of cellular mechanisms which resulted from Meyerhof’S work on muscle, and the impact which they had on biology as a whole. These notions have inspired and deeply influenced the investigations to be presented in this lecture, i.e., on the properties and function of proteins and enzymes of excitable membranes associated with the permeability changes during electrical activity and involved in the conduction of nerve impulses. The feelings of affection of the writer for his teacher and friend have been expressed on several occasions [1–3]. Due to his remarkable personality, Meyerhof attracted an unusual group of people. Even before joining Meyerhof, the writer was fortunate to have worked with H. H. Weber, who greatly advanced his knowledge of the physical chemistry of proteins. Among the contemporaries in Meyerhof’S laboratory were Severo Ochoa, Fritz Lipmann, Karl Lohmann, Hermann Blaschko. The frequent and stimulating discussions between the members of this group in addition to those with Meyerhof had an important influence on their thinking. Moreover, the inspiring atmosphere and the sharing of ideas favored the formation of strong bonds of friendship.

This lecture is based on the Lead Article in Science 168, 1959 (1970). — This work has been supported in part by grants from the U.S. Public Health Service Nos. NS-03304 and NS-07743, by the National Science Foundation, Grant No. NSF-GB-25362, and by the New York Heart Association, Inc.

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Author information

Authors and Affiliations

  1. Departments of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA

    David Nachmansohn

  2. Department Biochemistry, College of Physicians and Surgeons, Columbia University, New York, NY, USA

    David Nachmansohn

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  1. David Nachmansohn
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Editor information

Editors and Affiliations

  1. Max-Planck-Institut für medizinische Forschung, 69 Heidelberg 1, Jahnstr. 29, Germany

    Hans H. Weber

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Nachmansohn, D. (1972). Bioenergetics and Properties and Function of Proteins in Excitable Membranes Associated with Bioelectrogenesis. In: Weber, H.H. (eds) Molecular Bioenergetics and Macromolecular Biochemistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65309-4_17

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  • DOI: https://doi.org/10.1007/978-3-642-65309-4_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65311-7

  • Online ISBN: 978-3-642-65309-4

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