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Book cover Lehrbuch der Physiologie in Einzeldarstellungen

Zusammenfassung

Diffusionsmethoden. Die N2O-Methode, 1945 von KETY u. SCHMIDT beschrieben, ist Standardmethode zur Bestimmung der Durchblutung des Gesamtgehirns. Sie beruht auf dem Diffusionsprinzip mit der Berechnungsgrundlage nach FICK. Das Prinzip der Methode ist im Kapitel Herz beschrieben. Entnahmeorte für die Blutproben sind beim Menschen irgendeine Arterie, meistens die leicht zu punktierende A. femoralis und der Bulbus venae jugularis.

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Literatur

  • Adolph, E. F.: General and specific characteristics of physiological adaptions. Amer. J. Physiol. 184, 18 — 28 (1956).

    PubMed  CAS  Google Scholar 

  • Agnoli, A.: Adaptation of CBF during induced chronic normooxic respiratory acidosis. Scand. J. clin. Lab. Invest., Suppl. 102, VIII: D (1968).

    Google Scholar 

  • Aizawa, T., Tazaki, Y., Gotoh, F.: Cerebral circulation in cerebrovascular disease. Wid. Neurol. 2, 635 — 648 (1961).

    CAS  Google Scholar 

  • Alexander, S.C., Wollman, H., Cohen, P. J., Chase, P. E., Melman, E., Behar, M.: Krypton85 and nitrous oxide uptake of the human brain during anesthesia. Anaesthesiology 26, 27 — 42 (1964).

    Google Scholar 

  • Baust, W.: Local blood flow in different regions of the brain-stem during natural sleep and arousal. Electroenceph. olin. Neurophysiol. 22, 365 — 372 (1967).

    CAS  Google Scholar 

  • Bayliss, W. M.: On the local reactions of the arterial wall to changes of internal pressure. J. Physiol. (Lond.) 28, 220 — 231 (1902).

    CAS  Google Scholar 

  • Bedford, T. H. B.: The effect of variations in the subarachnoid pressure on the venous pressure in the superior longitudinal sinus and in the torcular of the dog. J. Physiol. (Lond.) 101, 362 — 368 (1942).

    CAS  Google Scholar 

  • Bell, R. L.: Observations of cerebral arterio-venous transit times using radio-iodinated human serum albumin. J. nucl. Med. 5, 9 — 15 (1964).

    PubMed  CAS  Google Scholar 

  • Bernsmeier, A.: Probleme der Hirndurchblutung. Z. Kreisl.-Forsch. 48, 278 — 323 (1959).

    CAS  Google Scholar 

  • Bernsmeier, A.: Zur Pathogenese cerebraler ZirkulationBBtürungen bei Erkrankungen des Herzens und der Lungen. Proceedings of the VII International Congress of Neurology, vol. 1, p. 291—315, Rom (1961).

    Google Scholar 

  • Bernsmeier, A., Gottstein, U.: Die Sauerstoffaufnahme des menschlichen Gehirns unter Phenothiacinen, Barbituraten und in der Ischämie. Pflügers Arch. ges. Physiol. 263, 102 — 108 (1956).

    CAS  Google Scholar 

  • BERNSMEIER, A., Hirndurchblutung und Alter. Verh. dtsch. Ges. Kreisl.-Forsch. 24, 248 — 253 (1958).

    Google Scholar 

  • Bernsmeier, A., Sack, H., Siemons, K.: Hochdruck und Hirndurchblutung (Unter besonderer Berücksichtigung der Augenhintergrundverii.nderungen und der neurologischen Komplikationen). Klin. Wschr. 32, 971 — 975 (1954).

    PubMed  CAS  Google Scholar 

  • Bernsmeier, A., Siemons, K.: Die Messung der Hirndurchblutung mit der Stickoxydulmethode. Pflügers Arch. ges. Physiol. 298, 149 — 162 (1953a).

    Google Scholar 

  • BERNSMEIER, A., Der Hirnkreislauf bei der gesteuerten experimentellen Hypotension Hypotension controlee). Schweiz. med. Wschr. 83, 210 — 212 (1953b).

    CAS  Google Scholar 

  • Bertha, H., Heppner, F., Jenker, F. L., Lechner, H., Rodler, R.: Zur Deutung des Schädelrheogrammes. Zbl. Neurochir. 19, 257 — 266 (1957).

    Google Scholar 

  • Betz, E.: Zur Registrierung der lokalen Gehirndurchblutung mit Wärmeleitsonden. Pflügers Arch. ges. Physiol. 284, 278 — 284 (1965a).

    CAS  Google Scholar 

  • Betz, E.: Adaption of regional cerebral blood flow in animals exposed to chronic alteration of p02 and pC02• Acta neurol. scand. 41, Suppl. 14, 121 — 128 (1965b).

    CAS  Google Scholar 

  • Betz, E.: Zur Pathophysiologie der Sauerstoffversorgung. Z. prakt. Anästh. Wiederbelebung 3, 261 — 272 (1968).

    Google Scholar 

  • Betz, E.: Local heat clearance from the brain as a measure of blood flow in acute and chronic experiments. Acta neurol. scand. 41, Suppl. 14, 29 — 37 (1965).

    CAS  Google Scholar 

  • Betz, E.: HENSEL, H.: Fortlaufende Registrierung der lokalen Durchblutung des Gehirns bei wachen, frei beweglichen Tieren. Pflügers Arch. ges. Physiol. 274, 608 — 614 (1962).

    Google Scholar 

  • Betz, E.: HERRMANN, E.: Die fortlaufende Registrierung der Gehirndurchblutung beim Menschen mit flexiblen Wii.rmeleitsonden. Nervenarzt 37, 173 — 175 (1966).

    CAS  Google Scholar 

  • Betz, E., Heuser, D.: Cerebral cortical blood flow during changes of acid-base equilibrium of the brain. J. appl. Physiol. 23, 726 — 733 (1967).

    PubMed  CAS  Google Scholar 

  • Betz, E., Ingvar,D.H., Lassen,N.A., Schmahl, F.W.: Regional blood flow in the cerebral cortex measured simultaneously by heat and inert gas clearance. Acta physiol. scand. 67, 1 — 9 (1966).

    PubMed  CAS  Google Scholar 

  • Betz, E., Kozak, R.: Der Einfluß der W asserstoffionenkonzentration der Gehirnrinde auf die Regulation der corticalen Durchblutung. Pfliigers Arch. ges. Physiol. 293, 56 — 67 (1967).

    CAS  Google Scholar 

  • Betz, E., Schmahl, F. W.: Durchblutung und Sauerstoffdruck in der Gehirnrinde bei Carotisdrosselung und ihre Beeinflussung durch Pharmaka. Pflügers Arch. ges. Physiol. 287, 368 — 384 (1966).

    CAS  Google Scholar 

  • Betz, E., Wullenweber, R.: Fortlaufende Registrierung der lokalen Gehirndurchblutung mit Wärmeleitsonden am Menschen. Klin. Wschr. 40, 1056 — 1058 (1962).

    PubMed  CAS  Google Scholar 

  • Birzis, L., Tachibana, S.: Measurement of local cerebral blood flow by impedance changes. Life Sci. 11, 587 - 598 (1962).

    Google Scholar 

  • Brobeil, A., Harter, 0., Herrmann, E., Nilsson, N. J.: MeBBungen von cerebralen Kreislaufzeiten am Menschen und ihre Beziehung zur Gehirndurchblutung. Acta physiol. scand. 40, 122 - 129 (1957).

    Google Scholar 

  • Brock, M., Ingvar, D. H., Jacobsen, C. W. S.: Regional blood flow in deep structures of the brain measured in acute cat experiments by means of a new beta-sensitive semiconductor needle detector. Exp. Brain Res. 4, 126 - 137 (1967).

    PubMed  CAS  Google Scholar 

  • Carlyle, A., Grayson, J.: Factors involved in the control of cerebral blood flow., J. Physiol. (Lond.) 133, 10 - 30 (1956).

    CAS  Google Scholar 

  • Cobb, S., Finesinger, J. E.: Cerebral circulation. XIX. The vagal pathway of the vasodilator impulses. Arch. Neurol. Psychiat. (Chic.) 28, 1243 - 1256 (1932).

    Google Scholar 

  • Creech, 0., Bresler, E., Halley, M., Adam, M.: Cerebral blood flow during extracorporeal circulation. Surg. Forum 8, 510 - 514 (1957).

    Google Scholar 

  • Cushing, H.: Some experimental and clinical observations concerning states of increased intracranial tension. Amer. J. med. Sci. 124, 375 - 400 (1902).

    Google Scholar 

  • Dewar, H. A., Davidson, L.A. G.: The cerebral blood flow in mitral stenosis and its response to carbon dioxide. Brit. Heart J. 20, 516 - 522 (1958).

    PubMed  CAS  Google Scholar 

  • Dewar, H. A., Owen, S. G., Jenkins, A. R.: Influence of tolazoline hydrochloride (Prisco!) on cerebral blood-flow in patients with mitral stenosis. Lancet 1953b, 867-870.

    Google Scholar 

  • Dieckhoff, D., Kanzow, E.: über die Lokalisation des Strömungswiderstandes im Hirnkreislauf. Pflügers Arch. 310, 75 - 85 (1969).

    PubMed  CAS  Google Scholar 

  • Diemer, K.: Über die Entwicklung der Gefäßversorgung im Sauglingsalter. Mschr. Kinderheilk. 112, 240 - 242 (1964).

    PubMed  CAS  Google Scholar 

  • Diemer, K.: Der Einflull chronischen Sauerstoffmangels auf die Capillarentwicklung im Gehirn des Sauglings. Mschr. Kinderheilk. 113, 281 - 283 (1965).

    PubMed  CAS  Google Scholar 

  • Diemer, K.: HENN, R.: Kapillarvermehrung in der Hirnrinde der Ratte unter chronischem Sauerstoffmangel. Naturwissenschaften 52, 135 - 136 (1965).

    Google Scholar 

  • Dumke, P.R., Schmidt, C. F.: Quantitative measurements of cerebral blood flow in the macacque monkey. Amer. J. Physiol. 138, 421 - 431 (1943).

    Google Scholar 

  • Ehrenreich, D. L., Burns, R. A., Alman, R. W., Fazekas, J. F.: Influence of acetazolamide on cerebral blood flow. Arch. Neurol. Psychiat. (Chic.) 5, 227 - 232 (1961).

    CAS  Google Scholar 

  • Eichhorn, 0.: Die Radiocirculographie, eine klinische Methode zur Messung der Hirndurchblutung. Wien. klin. Wschr. 71, 499 - 502 (1959).

    Google Scholar 

  • Falck, B., Mchedlishvili, G. I., Owman, Ch.: Histochemical demonstration of adrenergic nerves in cortex-pia of rabbit. Acta pharmacol. (Kbh.) 23, 133 - 142 (1965).

    CAS  Google Scholar 

  • Fazekas, J. F., Alman, R. W., Bessman, A. N.: Cerebral physiology of the aged. Amer. J. med. Sci. 223, 245 - 257 (1953).

    Google Scholar 

  • Fazekas, J. F., Bessman, A. N., Cotsonas, N. J., Alman, R. W.: Cerebral hemodynamics in cerebral arteriosclerosis. J. Geront. 8, 137 - 144 (1953).

    CAS  Google Scholar 

  • Fazekas, J. F., Mchenry, L. C., Alman, R. W., Sullivan, J. F.: Cerebral hemodynamics during brief hyperventilation. Arch. Neurol. Psychiat. (Chic.) 4, 132 - 138 (1961).

    CAS  Google Scholar 

  • Fedoruk, S., Feindel, W.: Measurement of brain circulation time by radioactive iodinated albumin. Canad. J. Surg. 3, 312 - 318 (1960).

    PubMed  CAS  Google Scholar 

  • Fieschi, C., Bozzao, L., Agnoli, A.: Regional clearance of hydrogen as a measure of cerebral blood flow. Acta neurol. scand., Suppl., 14, 46 - 52 (1965).

    CAS  Google Scholar 

  • Fieschi, C., Nardini, M., Bartolini, A.: The hydrogen method of measuring local blood flow in subcortical structures of the brain: Including a comperative study with the 14C antipyrine method. Exp. Brain Res. 7, lll-ll9 (1969).

    Google Scholar 

  • Finnerty, F. A., Guillaudeu, R. L., Fazekas, J. F.: Cardiac and cerebral hemodynamics in drug induced postural collapse. Circulat. Res. 5, 34 - 39 (1957).

    Google Scholar 

  • Finnerty, F. A., Witkin, L., Fazekas, J. F.: Cerebral hemodynamics during cerebral ischemia induced by acute hypotension. J. clin. Invest. 33, 1227 - 1232 (1954).

    PubMed  Google Scholar 

  • Florey, H.: Microscopical observation on the circulation of blood in the cerebral cortex. Brain 48, 43 - 64 (1925).

    Google Scholar 

  • Fog, M.: Om piaarteriernes vasomotoriske reaktioner. Munksgaard: Kiipenhamm 1934.

    Google Scholar 

  • Fog, M.: Cerebral circulation. The reactions of the pial arteries to a fall in blood pressure. Arch. Neurol. Psychiat. 37, 351 - 364 (1937).

    Google Scholar 

  • Fog, M.: The relationship between the blood pressure and the tonic regulation of the pial arteries. J. Neurol. Psychiat. 1, 187 - 197 (1938).

    CAS  Google Scholar 

  • Fog, M.: Cerebral circulation. I. Reaction of pial arteries to Epinephrine by direct application and by intravenous injection. Arch. Neurol. Psychiat. (Chic.) 41, 109-ll8 (1939a).

    Google Scholar 

  • Fog, M.: Cerebral circulation. II. Reaction of pial arteries to increase in blood pressure. Arch. Neurol. Psychiat. (Chic.) 41, 260 - 268 (1939b).

    Google Scholar 

  • Folkow, B.: Description of the myogenic hypothesis. Circulat. Res. 15, Suppl. I, 279 - 287 (1964).

    Google Scholar 

  • Forbes, H. S.: The cerebral circulation. I. Observation and measurement of pial vessels. Arch. Neurol. Psychiat. (Chic.) 19, 751 - 761 (1928).

    Google Scholar 

  • Forbes, H. S.: Regulation of the cerebral vessels - new aspects. Arch. Neurol. Psychiat. (Chic.) 80, 689 - 695 (1958).

    CAS  Google Scholar 

  • Forbes, H. S.: CoBB, ST. S.: Vasomotor control of cerebral vessels. Brain 61, 221 - 233 (1938).

    Google Scholar 

  • Forbes, H. S., Nason, G. I., Wortman, R. C.: Cerebral circulation. XLIV. Vasodilation in the pia following stimulation of the vagus, aortic and carotid sinus nerves. Arch. Neurol. Psychiat. (Chic.) 37, 334 - 350 (1937).

    Google Scholar 

  • Forbes, H. S., Schmidt, C. F., Nason, G. I.: Evidence of vasodilator innervation in the parietal cortex of the cat. Amer. J. Physiol. 129, 216 - 219 (1939).

    Google Scholar 

  • Forbes, H. S., Wolff, H. G.: Cerebral circulation. III. The vasomotor control of cerebral vessels. Arch. Neural. Psychiat. (Chic.) 19, 1057 - 1086 (1928).

    Google Scholar 

  • Ganshirt, H., Tonnis, W.: Durchblutung und Sauerstoffverbrauch des Hirns bei intracraniellen Tumoren. Dtsch. Z. Nervenheilk. 174, 305 - 330 (1956).

    CAS  Google Scholar 

  • Geiger, A., Sigg, E. B.: The significance of the hypothalamus in the regulation of the metabolism of the brain. Trans. Amer. neurol. Ass. 80, 117 - 120 (1955).

    Google Scholar 

  • GÉRaud, J., BÈS, A., Rascol, A., Delpla, M., Marc-Vergnes, J.P.: Mesure du debit sanguin cerebral au krypton 85. Quelques applications physio-pathologiques et cliniques. Rev. neurol. 108, 542 - 557 (1963).

    Google Scholar 

  • Gercken, G., Roth, E.: Metabolitkonzentration im Gehirn und Stromstarke-Druckabhangigkeit bei künstlicher Perfusion des Kaninchenkopfes. Pflügers Arch. ges. Physiol. 273, 589 - 603 (1961).

    CAS  Google Scholar 

  • Gibbs, F. A.: A thermoelectric blood flow recorder in the form of a needle. Proc. Soc. exp. Bioi. (N.Y.) 31, 141 - 147 (1933).

    Google Scholar 

  • Gibbs, F. A.: MAXWELL, H., GIBBS, E. L.: Volume flow of blood through the human brain. Arch. Neurol. Psychiat. (Chic.) 97, 137 - 144 (1947).

    Google Scholar 

  • Gleichmann, U., Ingvar, D. H., Lassen, N. A., LÜBbers, D. W., Siesjo, B. K., Thews, G.: Regional cerebral cortical metabolic rate of oxygen and carbon dioxide, related to the EEG in the anesthetized dog. Acta physiol. scand. M, 82 - 94 (1962).

    Google Scholar 

  • Gotoh, F., Meyer, J. S., Takagi, Y.: Cerebral effects of hyperventilation in man. Arch. Neural. Psychiat. 12, 410 - 423 (1965).

    CAS  Google Scholar 

  • Gotoh, F.,Tomita, M.: Carbonic anhydrase inhibition and cerebral venous blood gases and ions in man. Arch. intern. Med. 117, 39 - 46 (1966a).

    Google Scholar 

  • GOTOH, F., Hydrogen method for determining cerebral blood flow in man. Arch. Neural. Psychiat. 19, 549 - 559 (1966b).

    Google Scholar 

  • Gottstein, U.: Der Hirnkreislauf unter dem Einfluß vasoaktiver Substanzen. Heidelberg: Rüthig 1962.

    Google Scholar 

  • Grant, F. C., Spitz, E. B., Shenkin, H. A., Schmidt, C. F., Kety, S. S.: The cerebral blood flow and metabolism in idiopathic epilepsy. Trans. Amer. neural. Ass. 72, 82 - 86 (1947).

    CAS  Google Scholar 

  • Green, H. D., Rapela, C. E., Conrad, M. C.: Resistance (conductance) and capacitance phenomena in vascular beds. In: Handbook of physiology, sect. II, Circulation, p. 935. Washington, D.C.: American Physiological Society 1963.

    Google Scholar 

  • Greitz, T.: A radiologic study of the brain circulation by rapid serial angiography of the carotid artery. Acta radial. (Stockh.) 140, 12 - 19 (1956).

    Google Scholar 

  • Grote, J., Kreuscher, M.: Die Sauerstoffversorgung des Hundegehirns. I. Mitteilung: Die cerebrale Durchblutung und Sauerstoffaufnahme. Zool. Anz. 179, 320 - 329 (1967).

    Google Scholar 

  • Gurdjian, E. S., Webster, J. E., Martin, F. A., Thomas, L. M.: Cinephotomicrography of the pial circulation. Arch. Neurol. Psychiat. (Chic.) 80, 418 - 430 (1958).

    CAS  Google Scholar 

  • HÄGgendal, E.: Effects of some vasoactive drugs on the vessels of cerebral grey matter in the dog. Acta physiol. scand. 66, Suppl. 258, 55 - 79 (1965).

    Google Scholar 

  • HÄGgendal, E. Johansson, B.: Effects of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow autoregulation in dogs. Acta physiol. scand. 66, Suppl. 258, 27 - 53 (1965).

    Google Scholar 

  • HÄGgendal, E. LÖFgren, L., Nilsson, N. J., Zwetnow, N.: Die Gehirndurchblutung bei experimentellen Liquordruckänderungen. Acta neurochir. (Wien) 16, 163 (1967).

    Google Scholar 

  • HÄGgendal, E. Nilsson, N.J., N.RbÄCk, B.: On the components of Kr85 clearance curves from the brain of the dog. Acta physiol. scand. 66, Suppl. 258, 5 - 25 (1965).

    Google Scholar 

  • HÄGGENDAL, E. Effect of blood corpuscle concentration on cerebral blood flow. Acta chir. scand., Suppl. 364, 3 - 12 (1966).

    Google Scholar 

  • HÄGgendal, E., NorbÄCk, B.: Effect of blood viscosity on cerebral blood flow. Acta chir. scand., Suppl. 364, 13 - 22 (1966).

    Google Scholar 

  • HÄFkenschiel, J. H., Crumpton, C. W., Friedland, C. K.: Cerebral oxygen consumption in essential hypertension. Constancy with age, severity of the disease, sex and variations of blood constituents, as observed in 101 patients. J. clin. Invest. 33, 63 - 69 (1954).

    PubMed  Google Scholar 

  • Hafkenschiel, J. H., Crumpton, C. W., Moyer, J. H.: The effect of intramuscular dihydro· ergocornine on the cerebral circulation in normotensive patients. J. Pharmacol. exp. Ther. 98, 144 - 146 (1950).

    PubMed  CAS  Google Scholar 

  • HÄFkenschiel, J. H., Crumpton, C. W., Friedland, C. K., Jeffers, Vl. A.: The effect of dihydroergocornine on the cerebral circulation of patients wit essential hypertension. J. clin. Invest. 28, 408 - 411 (1950).

    Google Scholar 

  • Hafkenschiel, J. H., Crumpton, C. W., Shenkin, H. A., Moyer, J. H., Zintel, H. A., Wendel, H., Jeffers, W. A.: Theeffects of twenty degree head-up tilt up:m the cerebral circulation of patients with arterial hypertension before and after sympathectomy. J. clin. Invest. 30, 793 - 798 (1951).

    PubMed  CAS  Google Scholar 

  • Hafkenschiel, J. H., Friedland, C. K., Zintel, H. A., Lincoln, N. K., Brandt, H., Merill, J.: The blood flow and oxygen concumption of the brain in patients with esRential hypertension before and after adrenalectomy. J. clin. Invest. 33, 57 - 62 (1954).

    PubMed  CAS  Google Scholar 

  • Halley, M. M., Reemtsma, K., Creech, 0.: Cerebral blood flow, metabolism, and brain volume in extracorporeal circulation. J. thorac. Surg. 36, 506 - 518 (1958).

    PubMed  CAS  Google Scholar 

  • Handa, J., Ishikawa, S., Huber, P., Meyer, J. S.: Experimental production of the „subclavian steal“: electromagnetic flow measurements in the monkey. Surgery 68, 703 - 712 (1965).

    Google Scholar 

  • Harmel, M. H., Hafkenschiel, J. H., Austin, G. M., Crumpton, C. W., Kety, S. S.: The effect of bilateral stellate ganglion block on the cerebral circulation in normotensive and hypertensive patients. J. clin. Invest. 28, 415 - 418 (1949).

    Google Scholar 

  • Harper, A. M.: The inter-relationship between aPco, and blood pressure in the regulation of blood flow through the cerebral cortex. Acta neurol. scand. 41, Suppl. 14, 94 - 103 (1965).

    CAS  Google Scholar 

  • Harper, A. M., Bell, R. A.: The effect of metabolic acidosis and alkalosis on the blood flow through the cerebral cortex. J. Neurol. Neurosurg. Psychiat. 26, 341 - 344 (1963).

    PubMed  CAS  Google Scholar 

  • Harper, A. M.: JACOBSEN, J., McDowALL, D. G.: The effect of hyperbaric oxygen on the blood flow through the cerebral cortex. In: LEDINGHAM, I. M. (ed.), Hyperbaric oxygenation. Edinburgh a. London: Livingstone Ltd. 1965.

    Google Scholar 

  • Hedlund, S., Ljundgreen, K., Berggren, B., Brundell, P. 0.: Scintillation detectors for determination of cerebral blood flow. Acta radio!. (Stockh.) 2, 51 - 64 (1964).

    CAS  Google Scholar 

  • Hedlund, S., Nylin, G.: Cerebral blood flow and circulation time studied with labelled erythrocytes. Arch. int. Pharmacodyn. 139, 503 - 511 (1962).

    CAS  Google Scholar 

  • Hellinger, F. R., Bloor, B. M., Mccutchen, J. J.: Total cerebral blood flow and oxygen consumption using the dye dilution method. J. Neurosurg. 19, 964 - 970 (1962).

    PubMed  CAS  Google Scholar 

  • Henry, J. P., Gauer, 0. H., Kety, S. S., Kramer, K.: Factors maintaining cerebral circulation during gravitational stress. J. clin. Invest. 20, 292 - 300 (1951).

    Google Scholar 

  • Heyman, A., Patterson, Jr., J. L., Duke, T. W.: Cerebral circulation and metabolism in sickle cell and other chronic anemias, with observations on the effects of oxygen inhalation. J. clin. Invest. 31, 824 (1952).

    Google Scholar 

  • Himwich, W. A., Hamburger, E., Mareska, K., Himwich, H. E.: Brain metabolism in man: unanesthetized and in pentothal narcosis. Amer. J. Psychiat. 103, 669 - 696 (1947).

    Google Scholar 

  • Hirsch, H., Gleichmann, U., Kristen, H., MagazinoviĆ, V.: Über die Beziehung zwischen 0 2-Aufnahme des Gehirns und 0 2-Druck im Sinusblut des Gehirns bei uneingeschränkter und eingeschrankter Durchblutung. Pflügers Arch. ges. Physiol. 273, 213 - 222 (1961).

    CAS  Google Scholar 

  • Hirsch, H., Grote, G., Schlosser, V.: Über den Einfluß von Hexobarbitursaure auf Sauerstoffverbrauch und Vulnerabilitat des Gehirns. Pflügers Arch. ges. Physiol. 272, 247 - 253 (1961).

    CAS  Google Scholar 

  • Hirsch, H., Korner, K.: Über die Druck-Durchblutungs-Relation der Gehirngefäße. Pflügers Arch. ges. Physiol. 280, 316 - 325 (1964).

    Google Scholar 

  • HØEdt-Rasmussen, K.: Regional cerebral blood flow in man measured externally following intra-arterial administration of Kr85 of Xe133 dissolved in saline. Acta neurol. scand. 41, Suppl. 14, 65 - 68 (1965).

    Google Scholar 

  • HØEdt-Rasmussen, K. Sveinsdottir, E., Lassen, N. A.: Regional cerebral blood flow in man determined by intra-arteriel injection of radioactive inert gas. Circulat. Res. 18, 237 - 247 (1966).

    Google Scholar 

  • Holmqvist, B., Ingvar, D. H., SiesjÖ, B.: Cerebral sympathetic vasoconstriction and EEG. Acta physiol. scand. 40, 146 - 160 (1957).

    PubMed  CAS  Google Scholar 

  • Homburger, E., Himwich, E. A., Etstein, E., York, G., Maresca, R., Himwich, H. E.: Effect of pentothal anesthesia on canine cerebral cortex. Amer. J. Physiol.147, 343-345(1946)

    Google Scholar 

  • Huber, P., Meyer, J. S., Handa, J., Ishikawa, S.: Electromagnetic flowmeter study of carotid and vertebral blood flow during intracranial hypertension. Acta neurochir. (Wien) 13, 37 - 63 (1965).

    CAS  Google Scholar 

  • Ingvar, D. H.: Cortical state of excitability and cortical circulation. In: Reticular formation of the brain. Boston, Mass.: Little Brown 1958.

    Google Scholar 

  • Ingvar, D. H. Cronquist, S., Ekberg, R., Risberg, J., H0Edt-Rasmussen, K.: Normal values of regional cerebral flow in man including flow and weight estimates of gray and white matter. Acta neurol. scand. 41, Suppl. 14, 72 - 78 (1965).

    CAS  Google Scholar 

  • Ingvar, D. H. Lassen, N. A.: Regional blood flow of the cerebral cortex determined by krypton85• Acta physiol. scand. 54, 325 - 338 (1962).

    Google Scholar 

  • Ingvar, D. H. Risberg, J.: Influence of mental activity upon regional cerebral blood flow in man. Acta neurol. scand. 41, Suppl. 14, 183 - 186 (1965).

    CAS  Google Scholar 

  • Ingvar, D. H. SÖDerberg, U.: A new method for measuring cerebral blood flow in relation to the electroencephalogram. Electroenceph. clin. Neurophysiol. 8, 403 - 412 (1956).

    CAS  Google Scholar 

  • Ishikawa, S., Handa, J., Meyer, J. S., Huber, P.: Haemodynamics of the circle of Willis and the leptomeningeal anastomoses: an electromagnetic flowmeter study of intracranial arterial occlusion in the monkey. J. Neurol. Neurosurg. Psychiat. 28, 124 - 136 (1965).

    CAS  Google Scholar 

  • Jenkner, F. L.: Rheoencephalography. Confin. neurol. (Basel) 19, 1 - 20 (1959).

    CAS  Google Scholar 

  • Jenkner, F. L.: Rheoencephalography. A method for the continuous registration of cerebrovascular changes. Springfield, III.: Thomas 1962.

    Google Scholar 

  • Kanzow, E.: Quantitative fortlaufende Messung von Durchblutungsi:inderungen in der Hirnrinde. Pflügers Arch. ges. Physiol. 273, 100-209 (1961 a).

    Google Scholar 

  • Kanzow, E.: GREGL, I. M., HELD, U. P., RICHTERING, I.: Vasomotorische Reaktionen in der Großhirnrinde bei der EEG-Arousal. Pflügers Arch. ges. Physiol. 273, 288-301 (1961 b).

    Google Scholar 

  • Kanzow, E., Krause, D.: Vasomotorik der Hirnrinde und EEG-Aktivität wacher, frei beweglicher Katzen. Pflügers Arch. ges. Physiol. 174, 447 - 458 (1962).

    Google Scholar 

  • Kanzow, E.: GREGL, I. M., KUHNEL, H.: Die Vasomotorik der Hirnrinde in den Phasen desynchronisierter EEGAktivitätim natürlichen Schlaf der Katze. PflügersArch. ges. Physiol. 274, 593 - 607 (1962).

    CAS  Google Scholar 

  • Kanzow, E. Reichel, K.: Apperzeptiv-affektive GefäßBreaktionen in der GroBhirnrinde. Pflügers Arch. ges. Physiol. 293, 19 - 33 (1967).

    CAS  Google Scholar 

  • Kennedy, C., Sokoloff, L.: An adaptation of the nitrous oxide methode to the study of the cerebral circulation in children; normal values for cerebral blood flow and cerebral metabolic rate in childhood. J. clin. Invest. 36, 1130 - 1137 (1957).

    PubMed  CAS  Google Scholar 

  • Kety, S. S.: Circulation and metabolism of the human brain in health and disease. Amer. J. Med. 8, 205 - 217 (1950).

    PubMed  CAS  Google Scholar 

  • Kety, S. S.: The theory and applications of the exchange ofinert gas at the lungs and tissues. Pharmacal. Rev. 3, 1 - 41 (1951).

    CAS  Google Scholar 

  • Kety, S. S.: Human cerebral blood flow and oxygen consumption as related to aging. J. chron. Dis. 3, 478 - 486 (1956).

    PubMed  CAS  Google Scholar 

  • Kety, S. S.: The cerebral circulation. In: Handbook of physiology, sect. I: Neurophysiology, vol. III. Washington, D.C.: American Physiological Society 1960.

    Google Scholar 

  • Kety, S. S.: HAFKENSCHIEL, J. H., JEFFERS, W. A., LEOPOLD, J. H., SHENKIN, H. A.: The blood flow, vascular resistance, and oxygen consumption of the brain in essential hypertension. J. clin. Invest. 27, 511 - 514 (1948).

    CAS  Google Scholar 

  • Kety, S. S., Schmidt, C. F.: The determination of cerebral blood flow in man by the use of nitrous oxide in low concentration. Amer. J. Physiol. 143, 53 - 66 (1945).

    CAS  Google Scholar 

  • Kety, S. S., Schmidt, C. F.: The effect of active and passive hyperventilation on cerebral blood flow, cerebral oxygen consumption, cardiac output, and blood pressure of normal young men. J. clin. Invest. 25, 107 - 119 (1946).

    Google Scholar 

  • Kety, S. S., Schmidt, C. F.: The nitrous oxide method for the quantitative determination of cerebral blood flow in man. Theory, procedure and normal values. J. clin. Invest. 27, 476 - 483 (1948a).

    Google Scholar 

  • Kety, S. S., Schmidt, C. F.: The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young man. J. clin. Invest. 27, 484 - 492 (1948b).

    CAS  Google Scholar 

  • Kety, S. S., Shenkin, H. A., Schmidt, C. F.: The effect of increasing intracranial pressure on cerebral circulatory functions in man. J. clin. Invest. 27, 493 - 499 (1948).

    Google Scholar 

  • King, B. D., Sokoloff, L., Wechsler, R. L.: The effects of l-epinephrine and l-nor-epinephrine upon cerebral circulation and metabolism in man. J. clin. Invest. 31, 273 (1952).

    PubMed  CAS  Google Scholar 

  • Kogure, K., Scheinberg, P., Reinmuth, O. M., Fujishima, M., Busto, R.: Mechanism of cerebral vasodilatation in hypoxia. J. appl. Physiol. 29, 223 - 229 (1970).

    PubMed  CAS  Google Scholar 

  • Kreuscher, H.: Die Gehirndurchblutung unter Neuroleptanaesthesie. Berlin-HeidelbergNew York: Springer 1967.

    Google Scholar 

  • Krogh, J.: A comparative study of the effect of cervical sympathetic stimulation on cerebral blood flow. Medical Research Foundation of Christian Plesner, Oslo, 1964.

    Google Scholar 

  • Krupp, P.: Cerebrale Durchblutung und elektrische Hirnaktivitat. Basel-Stuttgart: Schwabe and Co. 1966.

    Google Scholar 

  • Kunert, W.: Über die Grundlagen der Schadelrheographie. Z. klin. Med. 196, 94 - 116 (1959).

    Google Scholar 

  • Lambertsen, C. J., Kough, R. H., Cooper, D. Y., Emmel, G. L., Loeschke, H. H., Schmidt, C. F.: Oxygen toxicity. Effects in man of oxygen inhalation at 1 and 3, 5 atmospheres upon blood gas transport, cerebral circulation and cerebral metabolism. J. appl. Physiol. 5, 471 - 486 (1953).

    PubMed  CAS  Google Scholar 

  • Landau, W. M., Freygang, W. H., Roland, L. P., Sokoloff, L., Kety, S. S.: The local circulation of the living brain; values in the unanesthetized and anesthetized cat. Trans. Amer. neural. Ass. 80, 125 - 129 (1955).

    Google Scholar 

  • Langfitt, T. W., Kassell, N. F., Weinstein, J. D.: Cerebral blood flow with intracranial hypertension. Neurology (Minneap.) 10, 761 - 773 (1965).

    Google Scholar 

  • Lassen, N. A.: Cerebral blood flow and oxygen consumption in man. Physiol. Rev. 39, 183 - 238 (1959).

    PubMed  CAS  Google Scholar 

  • Lassen, N. A., Feinberg, I., Lane, M. H.: Bilateral studies of cerebral oxygen uptake in young and aged normal subjects and in patients with organic dementia. J. clin. Invest. 39, 491 - 500 (1960).

    PubMed  CAS  Google Scholar 

  • Lassen, N. A. Hoedt-Rasmussen, K., Sorensen, S. C., Skinhoj, E., Cronquist, S., Badforss, B., Ingvar, D. H.: Regional cerebral blood flow in man determined by krypton85 Neurology (Mineap.) 13, 719 - 727 (1963).

    CAS  Google Scholar 

  • Lassen, N. A. Munck, O.: The cerebral blood flow in man determined by the use of radioactive krypton. Acta physiol. scand. 33, 30 - 49 (1955).

    PubMed  CAS  Google Scholar 

  • Lewis, B. M., Sokoloff, L., Wechsler, R. L., Wentz, W. B., Kety, S. S.: A method for the continuous measurement of cerebral blood flow in man by means of radioactive krypton (KR79). J. clin. Invest. 39, 707 - 716 (1957).

    Google Scholar 

  • Lierse, W.: Die Kapillardichte im Wirbeltiergehirn. Acta anat. (Basel) M, 1-31 (1963).

    Google Scholar 

  • Linden, L.: The effect of stellate ganglion block on cerebral circulation in cerebrovascular accidents. Acta med. scand., Suppl. 301 (1955).

    Google Scholar 

  • Ljundgreen, K., Nylin, G., Berggreen, B., Hedlund, S., Regnstron, O.: Observation on the determination of blood passage times in the brain by means of radioactive erythrocytes and externally placed detectors. Int. J. appl. Radiat. 12, 55 - 59 (1961).

    Google Scholar 

  • Loman, J., Dameshek, W., Myerson, A., Goldman, D.: Effect of alterations in posture on the intra-arterial blood pressure in man. Arch. Neurol. Psychiat. (Chic.) 35, 1216 - 1224 (1936).

    Google Scholar 

  • Ludwigs, N.: Über eine Modifikation der Methode nach GIBBS zur lokalisierten Durchblutungsmessung des Hirngewebes und die Giiltigkeit der damit erhobenen Befunde. Pflügers Arch. ges. Physiol. 299, 35 - 42 (1954).

    Google Scholar 

  • Ludwigs, N.: SCHNEIDER, M.: Über den Einfluß des Halssympathicus auf die Gehirndurchblutung. Pflügers Arch. ges. Physiol. 259, 43 - 55 (1954).

    CAS  Google Scholar 

  • Ludwigs, N.: WIEMERS, K.: Zur Hamodynamik der Hirndurchblutung bei Liquordrucksteigerung. Verh. dtsch. Ges. Kreisl.-Forsch. 19, 96 - 99 (1953).

    Google Scholar 

  • LÜBbers, D. W., Kessler, M., Knaust, K., Mcdowall, D. G., Womck, R.: Die Verwendung von W asserstoff und Sauerstoff zur Messung der lokalen Gewebedurchblutung in situ mit der Platinelektrode. Pflügers Arch. ges. Physiol. 289, R 99 (1966).

    Google Scholar 

  • Mangold, R., Sokoloff, L., Conner, E., Kleinermann, J., Therman, P. G., Kety, S. S.: The effect of sleep and lack of sleep on the cerebral circulation an the metabolism of normal young men. J. clin. Invest. 34, 1092 - 1100 (1955).

    PubMed  CAS  Google Scholar 

  • Mccall, M. L.: Cerebral circulation and metabolism in toxemia of pregnancy. Observations on the effects of Veratrum V iride and apresoline (1-hydrazinophthalazine). Amer. J. Obstet. Gynec. 66, 1015 - 1030 (1953).

    Google Scholar 

  • Mccall, M. L., Taylor, H. W.: The action of hydergine on the circulation and metabolism of the brain in toxemia of pregnancy. Amer. J. med. Sci. 226, 537 - 540 (1953).

    Google Scholar 

  • Mcdowall, D. G.: Interrelationship between blood oxygen tensions and cerebral blood flow. In: PAYNE, J.P. and D. H. HILL (eds.), A Symposium on Oxygen Measurements in Blood and Tissues and their Significance. London: J. and A. Churchill Ltd. 1966.

    Google Scholar 

  • Mchedlishvili, G. 1., Nikolaishvili, L. S.: Zum nervösen Mechanism us der funktionellen Dilatation der Piaarterien. Pflügers Arch. ges. Physiol. 296, 14 - 20 (1967).

    Google Scholar 

  • Mchenry, L.: Quantitative cerebral blood flow determination. Application of a krypton 85 desaturation technique in man. Neurology (Minneap.) 14, 785 - 793 (1964).

    Google Scholar 

  • Mercker, H., Opitz, E.: Die Gefäße der Pia mater hiihenangepaBter Kaninchen. Pflügers Arch. ges. Physiol. 251, 117 - 122 (1949).

    Google Scholar 

  • Mercker, H., Schneider, M.: Über Capillarveranderungen des Gehirns bei Hiihenanpassung. Pflügers Arch. ges. Physiol. 251, 49 - 55 (1949).

    Google Scholar 

  • Meyer, J. S., Gotho, F., Tazaki, Y.: Inhibitory action of carbon dioxide and acetazoleamide in seizure activity. Electroenceph. clin. Neurophysiol. 13, 762 - 775 (1961).

    CAS  Google Scholar 

  • Meyer, J. S., Gotho, F., Tomita, M., Akiyama, M.: Automatic recording of cerebral blood flow by the nitrous oxide method without blood loss. Ann. N.Y. Acad. Sci. 133, 305 (1966).

    Google Scholar 

  • Meyer, J. S., Ishikawa, S., Lee, T. K.: Electromagnetic measurement of internal jugular venous flow in the monkey. Effect of epilepsy and other procedures. J. Neurosurg. 21, 524 - 529 (1964).

    PubMed  CAS  Google Scholar 

  • Meyer, J. S., Gotho, F., Thal, A.: Quantitative measurement of cerebral blood flow with electromagnetic flowmeters. Trans. Amer. neural. Ass. 88, 78 - 83 (1963).

    CAS  Google Scholar 

  • Meyer, J. S., Nomura, F., Sakamoto, K., Kondo, A.: Effect of stimulation of the brain-stem reticular formation on cerebral blood flow and oxygen consumption. Electroenceph. clin. Neurophysiol. 26, 125 - 133 (1969).

    CAS  Google Scholar 

  • Mithoefer, J. C., Davis, J. S.: Inhibition of carbonic anhydrase: Effect in tissue gas tensions in the rat. Proc. Soc. exp. Bioi. (N.Y.) 98, 797 - 801 (1958).

    CAS  Google Scholar 

  • Mithoefer, J. C., Mayer, P. W., Stocks, J. F.: Effect of carbonic anhydrase on the cerebral circulation of the unanesthetized dog. Fed. Proc. 16, 382 - 383 (1957).

    Google Scholar 

  • Molnar, L.: Donnees recentes sur Ia regulation du debit sanguin cerebral. Actualites Neurophysiol. 7, 217 - 238 (1967).

    PubMed  CAS  Google Scholar 

  • Morris, G. C., Moyer, S. H., Snyder, H. B., Haynes, B. W.: Cerebral hemodynamics in controlled hypotension. Surg. Forum 4, 140-143 (1954).

    Google Scholar 

  • Moyer, J. H., Miller, S. I., Snyder, H.: Effect of increased jugular pressure on cerebral hemodynamics. J. appl. Physiol. 7, 245 - 247 (1954).

    PubMed  CAS  Google Scholar 

  • Moyer, J. H., Morris, G.: Cerebral hemodynamics during controlled hypotension induced by the continuous infusion of ganglionic blocking agents (Hexamethonium, Pendiomide and Arfonad). J. clin. Invest. 33, 1081 - 1088 (1954).

    PubMed  CAS  Google Scholar 

  • Moyer, J. H., Miller, S. I., Snyder, H., Smith, C. P.: A comparsion of the cerebral hemodynamic response to aramine and norepinephrine in the normotensive and the hypotensive subject. Circulation 10, 265 - 270 (1954).

    PubMed  CAS  Google Scholar 

  • Snyder, H., Miller, S. I., Smith, C. P.: Cerebral hemodynamic response to blood pressure reduction with phenoxybenzamine (Dibenzyline 688A). Amer. J. rued. Sci. 288, 563 (1954).

    Google Scholar 

  • Nelson, D., Fazekas, J. F.: Cerebral blood flow in polycythemia vera. Arch. intern. Med. 98, 328 - 330 (1956).

    Google Scholar 

  • Nilsson, N. J.: Eine oximetrische Methode zur Kreislaufzeitmessung am menschlichen Gehirn. Acta physiol. scand. 40, 84 - 100 (1957).

    Google Scholar 

  • Noell, W.: Über die Durchblutung und die Sauerstoffversorgung des Gehirns. V. Mitteilung. Einfluß der Blutdrucksenkung. Pflügers Arch. ges. Physiol. 247, 528 - 552 (1944a).

    CAS  Google Scholar 

  • Noell, W.: Uber die Durchblutung und Sauerstoffversorgung des Gehirns. VI. Mitteilung. Einfluß der Hypoxamie und Anamie. Pflügers Arch. ges. Physiol. 247, 553 - 575 (1944b).

    CAS  Google Scholar 

  • Schneider, M.: Über die Durchblutung und Sauerstoffversorgung des Gehirns im akuten Sauerstoffmangel. I. Mitteilung. Die Gehirndurchblutung. Pflügers Arch. ges. Physiol. 246, 181 - 200 (1942).

    Google Scholar 

  • Schneider, M.: Über die Durchblutung und die Sauerstoffversorgung des Gehirns. IV. Mitteilung. Die Rolle der Kohlensaure. Pflügers Arch. ges. Physiol. 247, 514 - 527 (1944).

    Google Scholar 

  • Schneider, M.: Quantitative Angaben über Durchblutung und Sauerstoffversorgung des Gehirns. Pflügers Arch. ges. Physiol. 250, 35 - 41 (1948a).

    Google Scholar 

  • Schneider, M.: Zur Hamodynamik der Gehirndurchblutung bei Liquordrucksteigerung. Arch. Psychiat. Nervenkr. 180, 713 - 730 (1948b).

    Google Scholar 

  • Novack, P., Shenkin, H. A., Bortin, L., Goluboff, B., Soffe, A.M.: The effects of carbon dioxide inhalation upon the cerebral blood flow and cerebral oxygen consumption in vascular disease. J. clin. Invest. 32, 696 - 702 (1953).

    PubMed  CAS  Google Scholar 

  • Nylin, G., Blomer, H., Jones, H., Hedlund, S., Rylander, C. G.: Further studies on the cerebral blood flow with thorium B- labelled erythrocytes. Brit. Heart. J. 18, 385 - 392 (1956).

    CAS  Google Scholar 

  • Nylin, G., Hedlund, S., Regnstrom, 0.: Studies of the cerebral circulation with labelled erythrocytes in healthy man. Circulat. Res. 9, 664 - 674 (1961).

    PubMed  CAS  Google Scholar 

  • Nylin, G., SilverskiÖLd, B. P., LÖFstedt, S., RegnstrÖM, 0., Hedlund, S.: Studies on cerebral blood flow in man, using radioactive-labelled erythrocytes. Brain 83, 293 - 335 (1960).

    PubMed  CAS  Google Scholar 

  • Opitz, E., Schneider, M.: tlber die Sauerstoffversorgung des Gehirns und den Mechanism us von Mangelwirkungen. Ergebn. Physiol. 46, 126 - 260 (1950).

    Google Scholar 

  • Patterson, J. L., Cannon, J. L.: Postural changes in the cerebral circulation, studied by continuous oxymetric and pressure-recording technique. J. clin. Invest. 30, 664 (1951).

    Google Scholar 

  • Patterson, J. L., Heyman, A., Battey, L. L., Ferguson, R. W.: Treshold of response of the cerebral vessels of man to increase in blood carbon dioxide. J. clin. Invest. 34, 1857 - 1864 (1955).

    PubMed  CAS  Google Scholar 

  • Patterson, J. L., Cannon, J. L. Duke, T.: Cerebral circulation and metabolism in chronic pulmonary emphysema. With observations on the effect of inhalation of oxygen. Amer. J. Med. 12, 363 387 (1952).

    Google Scholar 

  • Patterson, J. L., Warren, J. V.: Mechanisms of adjustment in the cerebral circulation upon assumption of the upright position. J. clin. Invest. 31, 653 (1952).

    Google Scholar 

  • Perez-Borja, C., Meyer, J. S.: A cortical evaluation of rheoencephatlography in control subjects and in proven cases of cerebrovascular disease. J. Neural. Neurosurg. Psychiat. 27, 66 - 72 (1964).

    Google Scholar 

  • Polzer, K., Schuhfried, F.: Rheographische Untersuchungen am Schadel. Wien. Z. Nervenheilk. 2, 295 - 297 (1951).

    Google Scholar 

  • PontÉN, N., SiesjÖ, B. K.: Brain tissue carbon dioxide changes and cerebral blood flow measurements. Acta neural. scand. 41, Suppl. 14, 129 - 134 (1965).

    Google Scholar 

  • Pool, J. L., Forbes, H. S., Nason, G. I.: Cerebral circulation. XXXII. Effect of stimulation of the sympathetic nerve on the pial vessels in the isolated head. Arch. Neural. Psychiat. (Chic.) 32, 915 - 923 (1934).

    Google Scholar 

  • Rapela, C. E., Green, H. D.: Autoregulation of canine cerebral blood flow. Circulat. Res. 15, Suppl. 1, 205 - 212 (1964).

    Google Scholar 

  • Reivich, M.: Arterial pC02 and cerebral hemodynamics. Amer. J. Physiol. 206, 25 - 35 (1964).

    PubMed  CAS  Google Scholar 

  • Rosomoff, N. L., Holaday, D. A.: Cerebral blood flow and cerebral oxygen consumption during hypothermia. Amer. J. Physiol. 179, 85 - 88 (1954).

    PubMed  CAS  Google Scholar 

  • Sagawa, K., Guyton, A. C.: Pressure flow relationships in isolated canine cerebral circulation. Amer. J. Physiol. 200, 711 - 714 (1961).

    PubMed  CAS  Google Scholar 

  • Scheinberg, P.: Cerebral blood flow in vascular disease of the brain. With observations on the effects of stellate ganglion block. Amer. J. Med. 8, 139 - 147 (1950).

    PubMed  CAS  Google Scholar 

  • Scheinberg, P., Stead, E. A.: The cerebral blood flow in male subjects as measured by the nitrous oxide technique. Normal values for blood flow, oxygen utilization, glucose utilization, and peripheral resistance, with observations on the effect of tilting and anxiety. J. clin. Invest. 28, 1163 - 1171 (1949).

    PubMed  CAS  Google Scholar 

  • Schieve, J. F., Wilson, W. P.: The influence of age, anesthesia and cerebral arteriosclerosis on cerebral vascular activity to C02 • Amer. J. Med. 15, 171 - 174 (1953).

    CAS  Google Scholar 

  • Schmidt, C. F.: The intrinsic regulation o£ the circulation in the hypothalamus of the cat. Amer. J. Physiol. 110, 137 - 152 (1934).

    CAS  Google Scholar 

  • SCHMIDT, C. F. The intrinsic regulation of the circulation in the parietal cortex of the cat. Amer. J. Physiol. 114, 572-585 (1935/36).

    Google Scholar 

  • Schmidt, C. F. Kety, S. S., Pennes, H. H.: The gaseous metabolism of the brain of the monkey. Amer. J. Physiol. 143, 33 - 52 (1945).

    CAS  Google Scholar 

  • Sensenbach, W., Madison, L., Ochs, L.: A comparision o£ effects of l-nor-epinephrine, synthetic l-epinephrine, and USP-epinephrine upon cerebral blood flow and metabolism in man. J. clin. Invest. 32, 226 - 232 (1953).

    PubMed  CAS  Google Scholar 

  • Serota, H., Gerard, R. W.: Localized thermal changes in the eat's brain. J. Neurophysiol. 1, 115 - 124 (1938).

    CAS  Google Scholar 

  • Severinghaus, J. W.: Outline of H+-b!ood £low relationship in brain. Scand. J. clin. Lab. Invest., Suppl. 102, VIII: K (1968).

    Google Scholar 

  • Severinghaus, J. W., Chiodi, H., Eger, E. I., Brandstater, B., Hornbein, T. F.: Cerebral blood flow in man at high altitude. Circulat. Res. 19, 274 - 282 (1966).

    PubMed  CAS  Google Scholar 

  • Severinghaus, J. W., Lassen, N.: Step hypocapnia to separate arterial from tissue pC02 in the regulation of cerebral blood flow. Circulat. Res. 20, 272 - 278 (1967).

    PubMed  CAS  Google Scholar 

  • SHENKIN, H. A., CABIESES, F., NOORDT, C. VAN DEN: The effect of bilateral stellectomy upon the cerebral circulation of man. J. clin. Invest. 30, 90 - 93 (1951).

    PubMed  CAS  Google Scholar 

  • Shenkin, H. A., Hafkenschiel, J. H., Kety, S. S.: Effects of sympathectomy on the cerebral circulation of hypertensive patients. Arch. Surg. 61, 319 - 324 (1950).

    PubMed  CAS  Google Scholar 

  • Shenkin, H. A., Harmel, M. H., Kety, S. S.: Dynamic anatomy of the cerebral circulation. Arch. Neurol. Psychiat. (Chic.) 60, 240 - 252 (1948).

    CAS  Google Scholar 

  • Shenkin, H. A., Novak, P., Goluboff, B., Soffe, A., Bortin, L.: The effects of aging, arteriosclerosis, and hypertension upon the cerebral circulation. J. clin. Invest. 32, 459 - 465 (1953).

    PubMed  CAS  Google Scholar 

  • Shenkin, H. A., Scheurman, M. G., Spitz, E. B., Groff, R. A.: Effect of change of position upon cerebral circulation of man. J. appl. Physiol. 2, 317 - 326 (1949).

    PubMed  CAS  Google Scholar 

  • Shenkin, H. A., Woodford, R. B., Freyhan, F. A., Kety, S. S.: The effects of frontal lobotomy on the cerebral blood flow and metabolism. Res. Publ. Ass. nerv. ment. Dis. 27, 823 - 831 (1948).

    CAS  Google Scholar 

  • Sokoloff, L.: Relation of cerebral circulation and metabolism to mental activity. In: KOREY, S. R., and J.l. NURNBERGER (eds.), Neurochemistry. New York: Hoeber-Harper 1956.

    Google Scholar 

  • Sokoloff, L.: Local cerebral circulation at rest and during altered cerebral activity induced by anesthesia or visual stimulation. In: KETY, S. S. and J. ELKES (eds.), Regional neurochemistry. Oxford: Pergamon Press 1961.

    Google Scholar 

  • Sokoloff, L.: MANGOLD, R., WECHSLER, R. L., KENNEDY, C., KETY, S. S.: The effects of mental arithmetric on cerebral circulation and metabolism. J. clin. Invest. 34, 1001-1008 (1955). SPUNDA, CH.: "Über den Wert und Anwendung der Schadelrheographie. Wien. klin. Wschr. 67, 788 - 792 (1955).

    Google Scholar 

  • Symon, L., Ishikawa, S., Lavy, S., Meyer, J. S.: Quantitative measurement of cephalic blood flow in the monkey. A study of vascular occlusion in the neck using electromagnetic flowmeters. J. Neurosurg. 20, 199 - 218 (1963).

    PubMed  CAS  Google Scholar 

  • Thompson, R. K., Malina, St.: Dynamic axial brain-stem distortion as a mechanism explaning the cardiorespiratory changes in increased intracranial pressure. J. Neurosurg. 16, 664 - 675 (1959).

    PubMed  CAS  Google Scholar 

  • Tonnis, W., Scmefer, W.: Zirkulationsstorungen des Gehirns im Serienangiogramm. BerlinGottingen- Heidelberg: Springer 1959.

    Google Scholar 

  • Turner, J., Lambertsen, C. J., Owen, S. G., Wendel, H., Chiodi, H.: Effects of.08 and.8 atmospheres of inspired p02 upon cerebral hemodynamics at a "constant" alveolar pC02 of 43 mm Hg. Fed. Proc. 16, 130 (1957).

    Google Scholar 

  • Veall, N., Mallett, B. L.: Regional cerebral blood flow determination by 133Xe inhalation and external recording: The effect of arterial recirculation. Clin. Sci. 30, 353 - 369 (1966).

    PubMed  CAS  Google Scholar 

  • Wilcke, G., Zeh, H.: Klinische und experimentelle Untersuchungen zur Bestimmung der Zirkulationszeit mit radioaktiven Isotopen. Zbl. Neurochir. 23, 145 - 152 (1963).

    CAS  Google Scholar 

  • Wilson, W. P., Odom, G. L., Durham, N. C., Scmeve, J. F.: The effect of carbon dioxide on cerebral blood flow, spinal fluid pressure and brain volume during pentothal sodium anesthesia. Curr. Res. Anesth. 32, 268 - 273 (1953).

    CAS  Google Scholar 

  • Wollman, H., Alexander, S.C., Cohen, P. J., Stephen, G. W., Zeiger, L. S.: TwoCompartment of the Blood Flow in the Human Brain. Acta neurol. scand. 41, Suppl. 14, 79 - 82 (1965).

    CAS  Google Scholar 

  • Wright, D.: Experimental observations on increased intracranial pressure. Aust. N.Z. J. Surg. 7, 215 - 235 (1938).

    Google Scholar 

  • Wullenweber, R.: Schwankungen der Hirndurchblutung unter physiologischen und pathophysiologischen Bedingungen. Acta neurochir. (Wien) 13, 64 - 76 (1965).

    CAS  Google Scholar 

  • Wullenweber, R., Schmitz-Valckenberg, P.: Zur Frage der nervosen Regulation der Hirndurchblutung. Acta neurochir. (Wien) 18, 95 - 111 (1968).

    Google Scholar 

  • Zierler, K. L.: Equations for measuring blood flow by external monitoring of radioisotopes. Circulat. Res. 16, 309 - 321 (1965).

    PubMed  CAS  Google Scholar 

  • ZIERLER, K. L., Circulation times and the theory of indicatordilution methods for determining blood flow and volume. In: Handbook od physiology, sect. II, vol. 1, p. 585 - 615. Washington: American Physiological Society 1962.

    Google Scholar 

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Erich Schütz E. Bauereisen H. Bartels R. D. Bauer E. Bauereisen K. Golenhofen G. Hauck H. Hirsch W. Lochner J. Lutz W. Moll Th. Pasch K. Thurau E. Wetterer J. Wolff

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Hirsch, H. (1971). Gehirn. In: Schütz, E., et al. Lehrbuch der Physiologie in Einzeldarstellungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65203-5_4

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