It is not within the scope of this monograph to discuss the chemical basis of drug metabolism in detail. This subject has been adequately covered by others in several excellent reviews (listed at the end of this chapter). Here we shall merely present a very succinct outline, followed by abstracts of key papers on enzymic reactions likely to participate in the metabolism of substrates that are influenced by adaptive hormones.
KeywordsMicrosomal Fraction Hepatic Microsome Fumarate Hydratase Mercapturic Acid Polycyclic Hydrocarbon
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