Skip to main content

Influence of Ethanol on the Metabolism of the Protein-deficient Fatty Liver

  • Chapter
Book cover Metabolic Changes Induced by Alcohol
  • 65 Accesses

Abstract

The liver is the chief organ concerned with the oxidation of ethanol (7). After alcohol passes from the blood into the liver cell it is first oxidized to acetaldehyde. This reaction is catalyzed by the enzyme alcohol dehydrogenase, which contains zinc; it is mainly located in the liver cytoplasm (11). Nicotin-amide adenine dinucleotide, NAD, functions as the coenzyme and hydrogen acceptor (Fig. 1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bücher, Th. and M. Klingenberg, Angew. Chem. 70, 552 (1958).

    Article  Google Scholar 

  2. Forsander, O.A., N. Räihä, M. Salaspuro, and P. Mäenpää, Biochem.J. 94, 259 (1965).

    CAS  Google Scholar 

  3. Forsander, O., N. Räihä, and H. Suomalainen, Z.Physiol.Chem. 312, 243 (1958).

    Article  CAS  Google Scholar 

  4. Freinkel, N., R.A. Arky, D.L. Singer, A.K. Cohen, S.J. Bleicher, J.B. Anderson, C.K. Silbert, and A.E. Foster, Diabetes 14, 350 (1965).

    PubMed  CAS  Google Scholar 

  5. Isselbacher, K.J. and S.M. Krane, J. Biol. Chem. 236, 2394 (1961).

    PubMed  CAS  Google Scholar 

  6. Krebs, H.A., R.A. Freedland, R. Hems, and Marion Stubbs, Biochem.J. 112, 117 (1969).

    PubMed  CAS  Google Scholar 

  7. Leloir, L.P. and J.M. Munoz, Biochem.J. 32, 299 (1938).

    PubMed  CAS  Google Scholar 

  8. Lieberman, F.L., Gastroenterology 44, 261 (1963).

    PubMed  CAS  Google Scholar 

  9. Lundquist, F., N. Tygstrup, K. Winkler, and K. Mellemgaard, J.Clin.Invest. 41, 955 (1962).

    Article  PubMed  CAS  Google Scholar 

  10. Mikata, A., A.A. Dimakulangan, and W.S. Hartroft, Gastroenterology 44, 159 (1963).

    PubMed  CAS  Google Scholar 

  11. Nyberg, A., J. Schuberth, and L. Änggard, Acta Chem.Scand. 7, 1170 (1953).

    Article  CAS  Google Scholar 

  12. Salaspuro, M.P., Scand.J.Clin.Lab.Invest. 20, 274 (1967).

    Article  Google Scholar 

  13. Salaspuro, M.P. and A. Kesäniemi, to be published.

    Google Scholar 

  14. Salaspuro, M.P. and P.H. Mäenpää, Biochem. J. 100, 768 (1966).

    PubMed  CAS  Google Scholar 

  15. Salaspuro, M.P. and A.E. Salaspuro, Scand.J.Clin.Lab.Invest. 22, 49 (1968).

    Article  PubMed  CAS  Google Scholar 

  16. Tygstrup, N. and F. Lundquist, J.Lab.Clin.Med. 59, 102 (1962).

    PubMed  CAS  Google Scholar 

  17. Williamson, D.H., P. Lund, and H.A. Krebs, Biochem.J. 103, 514 (1967).

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Salaspuro, M.P. (1971). Influence of Ethanol on the Metabolism of the Protein-deficient Fatty Liver. In: Martini, G.A., Bode, C. (eds) Metabolic Changes Induced by Alcohol. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65131-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-65131-1_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-05296-8

  • Online ISBN: 978-3-642-65131-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics