Skip to main content

Immunology of Reproduction

  • Conference paper
Mammalian Reproduction

Abstract

Among the different topics in the field of immunoreproduction, immunologic factors of human sterility and infertility are of special clinical interest.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. ANDRESEN, R. H., MONROE, C. W.: Experimental study of the behaviour of adult human skin homografts during pregnancy. Amer. J. Obstet. Gynec. 84, 1096 (1962).

    PubMed  CAS  Google Scholar 

  2. BANDHAUER, K., MARBEBGER, E., MARBEBGEB, H.: Immunologische Einflüsse auf männliche Fertilitätsstörungen. Urologe 3, 222 (1964).

    Google Scholar 

  3. BANDHAUER, K.: Immunreaktionen bei Fertilitätsstörungen des Mannes. Urol. Int. 21, 247 (1966).

    Article  PubMed  CAS  Google Scholar 

  4. BARDAWIL, W. A., TOY, B. L.: The natural history of choriocarcinoma: problems of immunity and spontaneous regression. Ann. N. Y. Acad. Sci. 80, 197 (1959).

    Article  PubMed  CAS  Google Scholar 

  5. BARDAWIL, W. A., MITCHELL, G. W., MCKEOGH, R. P., MARCHANT, O. J.: Behaviour of skin homografts in human pregnancy I. Habitual abortion. Amer. J. Obstet. Gynec. 84, 1283 (1962).

    PubMed  CAS  Google Scholar 

  6. BEHRMAN, S. J., AMANO, Y.: Immunochemical studies on human seminal plasma. Int. J. Fert. 12, 291 (1967).

    CAS  Google Scholar 

  7. BILLINGHAM, R. E., LAMPKIN, G. H.: Further studies in tissue homotransplantation in cattle. J. Embryol. exp. Morph. 5, 351 (1957).

    Google Scholar 

  8. BILLINGHAM, R. E., SILVERS, W. K.: Skin transplants and the hamster. Sci. Amer. 208, 118 (1963).

    Article  PubMed  CAS  Google Scholar 

  9. BILLINGHAM, R. E.: Transplantation immunity and the maternal-fetal relation. New Engl. J. Med. 270, 667 (1964).

    CAS  Google Scholar 

  10. BOSS, J. H.: The antigen distribution pattern of the human placenta. Lab. Invest. 12, 332 (1963).

    PubMed  CAS  Google Scholar 

  11. BOYDEN, S.: The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. J. exp. Med. 93, 107 (1951).

    Article  PubMed  CAS  Google Scholar 

  12. BRADBURY, S., BILLINGTON, W. D., KIRBY, D. R. S.: A histochemical and electron microscopical study of the fibroid of the mouse placenta. J. roy. micr. Soc. 84, 199 (1965).

    Article  PubMed  CAS  Google Scholar 

  13. COHEN, B. H., SAYRE, J. E.: Further observations on the relationship of maternal ABO and Rh types to fetal death. Amer. J. hum. Genet. 20, 310 (1968).

    PubMed  CAS  Google Scholar 

  14. COOMBS, R. R. A., EDWARDS, R. G., GURNER, B. W.: Cited in: Brit, med. Bull. 26, 72 (1970) by EDWARDS, R. G.: Immunology of conception and pregnancy.

    Google Scholar 

  15. CRONQUIST, S.: Spermatic invasion of the epididymis. Acta path, microbiol. scand. 26, 786 (1949).

    Article  Google Scholar 

  16. CURRIE, G. A., DOORNINCK, W. V., BAGSHAWE, K. D.: Effect of neuraminidase on the immunogenicity of early mouse trophoblast. Nature (Lond.) 219, 191 (1968).

    Article  CAS  Google Scholar 

  17. CURZEN, P.: The antigenicity of the human placenta. Proc. roy. Soc. Med. 63, 65 (1970).

    PubMed  CAS  Google Scholar 

  18. DOUGHERTY, T. E., BERLINER, M. L., SCHNECBELI, G. L., BERLINER, D. L.: Hormonal control of lymphatic structure and function. Ann. N. Y. Acad. Sci. 113, 825 (1964).

    Article  PubMed  CAS  Google Scholar 

  19. DOUGLAS, G. W., THOMAS, L., CARR, M., CULLEN, N. M., MORRIS, M.: Trophoblast in the circulating blood during pregnancy. Amer. J. Obstet. Gynec. 78, 960 (1959).

    PubMed  CAS  Google Scholar 

  20. DOUGLAS, G. W.: The immunologic role of the placenta. Obstet. Gynec. Survey 20, 442 (1965).

    Article  PubMed  CAS  Google Scholar 

  21. DUBRAUSZKY, V.: Personal communication.

    Google Scholar 

  22. EDWARDS, R. G.: Transmission of antibodies across membranes of the reproductive tract. In: EDWARDS, R. G., Immunology and reproduction, Hertford: Stephan Austin and Sons, Ltd. 1969.

    Google Scholar 

  23. EDWARDS, R. G.: Immunology of conception and pregnancy. Brit, med. Bull. 26, 72 (1970).

    PubMed  CAS  Google Scholar 

  24. EYQUEM, A., JOUANNE, C., LANDBEIN, S.: Contribution a l’étude des constituants antigéniques du plasma seminal humain. Ann. Inst. Pasteur 110, 89 (1966).

    Google Scholar 

  25. FELTKAMP, F. E. W., KBUYFF, K., LADIGES, N. C. J. J., RÜMKE, P.: Auto-spermagglutinins. II. Immunofluorescent studies. Ann. N. Y. Acad. Sci. 124, 702 (1965).

    Article  PubMed  CAS  Google Scholar 

  26. FJÄLLBRANT, B.: Sperm antibodies and sterility in men. Acta obstet. gynec. scand. 47, Suppl. 4, 1 (1968).

    Article  Google Scholar 

  27. FRANKLIN, R. R., DUKES, C. D.: Further studies on sperm-agglutinating antibody and unexplained infertility. J. Amer. med. Ass. 190, 682 (1964).

    CAS  Google Scholar 

  28. FRANKLIN, R. R., DUKES, C. D.: Antispermatozoal antibody and unexplained infertility. Amer. J. Obstet. Gynec. 89, 6 (1964).

    PubMed  CAS  Google Scholar 

  29. FRIEDMAN, N. B., GARSKE, G. L.: Inflammatory reactions involving sperm and the seminiferous tubules: extravasation spermatic granulomas and granulomatous orchitis. J. Urol. (Baltimore) 62, 363 (1949).

    CAS  Google Scholar 

  30. GERMUTH, F. G.: The role of adrenocortical steroids in infection immunity and hypersensitivity. Pharmacol. Rev. 8, 1 (1956).

    PubMed  CAS  Google Scholar 

  31. GROSS, S. J.: The current dilemma of placental antigenicity. Obstet. Gynec. Survey 25, 105 (1970).

    Article  Google Scholar 

  32. HALPERN, B. N., KYAND, T., ROBERT, B.: Clinical and immunological study of an exceptional case of reaginic type sensitization to human seminal fluid. Immunology 12, 247 (1967).

    PubMed  CAS  Google Scholar 

  33. HEKMAN, A., RÜMKE, P.: The antigens of human seminal plasma. Fertil. Steril. 20, 312 (1969).

    PubMed  CAS  Google Scholar 

  34. HESLOP, R. W., KBOHN, P. L., SPABBOW, E. M.: The effect of pregnancy on the survival of skin homografts in rabbits. J. Endocr. 10, 325 (1954).

    Article  PubMed  CAS  Google Scholar 

  35. HULKA, J. F., HSU, K. C., BEISEB, J. M.: Antibodies to trophoblast during the post-partum period. Nature (Lond.) 191, 510 (1961).

    Article  CAS  Google Scholar 

  36. HULKA, J. F., BRINTON, V., SCHAAF, J., BANEY, C.: Appearance of antibodies to trophoblast during the post-partum period in normal human pre-gnancies. Nature (Lond.) 198, 501 (1963).

    Article  CAS  Google Scholar 

  37. IKLÉ, A.: Trophoblastzellen im strömenden Blut. Schweiz. med. Wschr. 91, 943 (1961).

    PubMed  Google Scholar 

  38. IKLÉ, A.: Dissemination von Syncytiotrophoblastzellen im mütterlichen Blut während der Gravidität. Bull. schweiz. Akad. med. Wiss. 20, 62 (1964).

    Google Scholar 

  39. ISOJIMA, S., LI, T. S., ASHITAKA, Y.: Immunologic analysis of sperm-immobilizing factor found in sera of women with unexplained sterility. Amer. J. Obstet. Gynec. 101, 677 (1968).

    Google Scholar 

  40. JANOVSKI, N.: Personal communication.

    Google Scholar 

  41. KAKU, M.: Placental polysacaharide and the aetiology of the toxaemia of pregnancy. J. Obstet. Gynec. Brit. Emp. 60, 148 (1953).

    Article  CAS  Google Scholar 

  42. KATSH, S.: In vitro demonstration of uterine anaphylaxis in guinea pigs sensitized with homologous testis or sperm. Nature (Lond.) 180, 1047 (1957).

    Article  CAS  Google Scholar 

  43. KATSH, S.: Demonstration in vitro and anaphylactoid response of the uterus and ileum of guinea pigs injected with testis or sperm. J. exp. Med. 101, 95 (1958).

    Article  Google Scholar 

  44. KERR, M. G.: Immunological rejection as a cause of abortion. J. Rep. Fert. Suppl. 3, 49 (1968).

    Google Scholar 

  45. KIBRICK, S., BELDING, D. L., MERRILL, B.: Methods for the detection of antibodies against mammalian spermatozoa. Fert. Steril. 3, 430 (1952).

    CAS  Google Scholar 

  46. KING, E. S. J.: Spermatozoa invasion of the epididymis. J. Path. Bact. 70, 459 (1955).

    Article  PubMed  CAS  Google Scholar 

  47. KIRBY, D. R. S., BILLINGTON, W. D., BRADBURY, S., GOLDSTEIN, D.: Antigen barrier of the mouse placenta. Nature (Lond.) 204, 548 (1964).

    Article  CAS  Google Scholar 

  48. KIRBY, D. R. S., BILLINGTON, W. D., JAMES, D. A.: Transplantation of eggs to the kidney and uterus of immunized mise. Transplantation 4, 713 (1966).

    Article  PubMed  CAS  Google Scholar 

  49. KIRBY, D. R. S.: Transplantation and pregnancy. In: RAPAPORT, F. T. and J. DAUSSET: Human transplantation, p. 565. New York: Grune and Stratton 1968.

    Google Scholar 

  50. KRIEG, H., KASPER, K.: Zur Frage der ABO-Inkompatibilität als Abortursache. Geburtsh. Frauenheilk. 27, 679 (1967).

    PubMed  CAS  Google Scholar 

  51. KRIEG, H.: Blood group substances and infertility. In: BATANOV, K.: Immun. Spermatozoa and Fertilization, p. 46. Varna: Bulgarian Acad. Sci. 1967.

    Google Scholar 

  52. KRIEG, H.: Immunologisch bedingte Fertilitatsstorungen. Med. Klin. 64, 1223 (1969).

    PubMed  CAS  Google Scholar 

  53. KRIEG, H.: Effect of blood group differences between parents on fertility and embryonic development. In: EDWARDS, R. G.: Immunology and reproduction, p. 234. Hertford: Stephen Austin and Sons, Ltd. 1969.

    Google Scholar 

  54. LANDSTEINER, K.: Zur Kenntnis der spezifisch auf Blutkörperchen wirkenden Sera. Zbl. Bakt. 25, 546 (1899).

    Google Scholar 

  55. LANMAN, J. T., DINERSTEIN, J., FIKRIG, S.: Homograft immunity in pregnancy: lack of harm to the fetus from sensitization of the mother. Ann. N. Y. Acad. Sci. 99, 706 (1962).

    Article  PubMed  CAS  Google Scholar 

  56. LANMAN, J. T.: Transplantation immunity in mammalian pregnancy, mechanisms of fetal protection against immunologic rejection. J. Pediat. 66, 525 (1965).

    Article  PubMed  CAS  Google Scholar 

  57. LEITHOFF, H., LEITHOFF, J.: Neue Ergebnisse immunoelektrophoretitischer Untersuchungen des menschlichen Samenplasmas. Med. Welt 4, 181 (1962).

    PubMed  CAS  Google Scholar 

  58. LITTLE, C. C.: Genetics of tissue-transplantation in mammals. J. Cancer. Res. 8, 75 (1924).

    Google Scholar 

  59. MARINE, D., MANLEY, O. T., BAUMANN, E. J.: Influence of thyroidectomy, gonadectomy, suprarenalectomy and splenectomy on thymus gland of rabbit. J. exp. Med. 40, 429 (1924).

    Article  PubMed  CAS  Google Scholar 

  60. MATSUNAGA, E., ITOH, S.: Blood groups and fertility in a Japanese population, with special reference to maternal-fetal incompatibility. Ann. hum. Genet. 22, 111 (1958).

    Article  PubMed  CAS  Google Scholar 

  61. MEDAWAR, P. B.: Immunity to homologous grafted skin. III. Fate of skin homografts transplanted to brain, to subcutaneous tissue and to anterior chamber of eye. Brit. J. exp. Path. 29, 58 (1948).

    PubMed  CAS  Google Scholar 

  62. MEDAWAR, P. B.: Some immunological and endocrinological problems raised by evolution of viviparity in vertebrates. In: Soc. for exp. Biology Evolution Symposia No. 11, pp. 320. New York: Academic Press, Inc. 1953.

    Google Scholar 

  63. MEDAWAR, P. B., SPARROW, E. M.: Effects of adrenocortical hormones, adrenocorticotropic hormone and pregnancy on skin transplantation immunity in mice. J. Endocr. 14, 240 (1956).

    Article  PubMed  CAS  Google Scholar 

  64. METCHNIKOFF, S.: Etudes sur la résorption des cellules. Ann. Inst. Pasteur 13, 737 (1899).

    Google Scholar 

  65. NELSON, J. H.: Alterations in immune mechanisms in pregnancy. Clin. Obstet. Gynec. 8, 263 (1965).

    Article  Google Scholar 

  66. OUCHTERLONY, O.: Antigen-antibody reactions in gels. Acta path, microbiol. scand. 26, 507 (1949).

    Article  CAS  Google Scholar 

  67. PARISH, W. E., WARD, A.: Studies of cervical mucus and serum from infertile women. J. Obstet. Gynec. Brit. Cwth 75, 1089 (1968).

    Article  CAS  Google Scholar 

  68. PHADKE, A. M.: Fate of spermatozoa in cases of obstructive azoospermia and after ligation of vas deferens in man. J. Rep. Fert. 7, 1 (1964).

    Article  CAS  Google Scholar 

  69. PRESSMAN, D., KORNGOLD, L.: Localizing of anti-placenta serum. J. Immunol. 78, 75 (1957).

    PubMed  CAS  Google Scholar 

  70. QUINLIVAN, W. L. G.: The specific antigens of human seminal plasma. Fert. Steril. 20, 58 (1969).

    CAS  Google Scholar 

  71. RAO, S. S.: Cited in: EDWARDS, R. G.: Immunology of reproduction, p. 170. Hertford: Stephan Austin and Sons Ltd. 1969.

    Google Scholar 

  72. REID, B. L.: The behaviour of human sperm towards cultured fragments of human cervix uteri. Lancet 21, 7323 (1964).

    Google Scholar 

  73. ROIG DE VARGAS-LINARES, C. E.: Plasma cells in the hamster vagina: cyclical and experimental variations. J. Rep. Fert. 15, 389 (1968).

    Article  Google Scholar 

  74. RÜMKE, P.: The presence of sperm antibodies in the serum of two patients with oligozoospermia. Yox. Sang. 4, 135 (1954).

    Google Scholar 

  75. RÜMKE, P., HELLINGA, G.: Auto-antibodies against spermatozoa in sterile men. Amer. J. clin. Path. 32, 357 (1959).

    Google Scholar 

  76. RÜMKE, P.: Sperm-agglutinating autoantibodies in relation to mile infertility. Proc. roy. Soc. Med. 61, 275 (1968).

    PubMed  Google Scholar 

  77. RÜMKE, P.: Clinical aspects of autoimmunity to spermatozoa in men. In: EDWARDS, R. G.: Immunology and reproduction, p. 251. Hertford: Stephen Austin and Sons Ltd. 1969.

    Google Scholar 

  78. SCHLESINGER, M.: Uterus of rodents as site for manifestation of trans-plantation immunity against transplantable tumors. J. nat. Cancer Inst. 28, 927 (1962).

    PubMed  CAS  Google Scholar 

  79. SCHLESINGER, M.: Serologic studies of embryonic and trophoblastic tissues of the mouse. J. Immunology 93, 255 (1964).

    CAS  Google Scholar 

  80. SCHOYSMAN, R.: Treatment of male infertility due to auto-agglutination of spermatozoa. Proc. 6 th World Congr. Fertility and Sterility, Tel Aviv, 112 (1968).

    Google Scholar 

  81. SCHWIMMER, W. B., USTAY, K. A., BEHRMAN, S. J.: An evaluation of immunologic factors of infertility. Fert. Steril. 18, 167 (1967).

    CAS  Google Scholar 

  82. SIMMONS, R. L., RUSSELL, P. S.: The antigenicity of mouse trophoblast. Ann. N. Y. Acad. Sci. 99, 717 (1962).

    Article  PubMed  CAS  Google Scholar 

  83. SIMMONS, R. L.: Failure to demonstrate immunological competence in term mouse placenta cells. Transplantation 2, 431 (1964).

    Article  PubMed  CAS  Google Scholar 

  84. SIMMONS, R. L., RUSSELL, P. S.: Histocompatibility antigens in transplanted mouse eggs. Nature (Lond.) 208, 698 (1965).

    Article  CAS  Google Scholar 

  85. SIMMONS, R. L.: Mechanisms of trophoblast non-antigenicity. Fed. Proc. 25, 356 (1966).

    Google Scholar 

  86. SIMMONS, R. L., RUSSELL, P. S.: The histocompatibility antigens of fertilized mouse eggs and trophoblast. Ann. N. Y. Acad. Sci. 129, 35 (1966).

    Article  Google Scholar 

  87. SIMMONS, R. L., RUSSELL, P. S.: Immunological interactions between mother and fetus. Adv. Obstet. Gynec. 1, 38 (1967).

    Google Scholar 

  88. SIMMONS, R. L.: Histoincompatibility on the survival of the fetus: current controversies. Transplantation Proc. 1, 47 (1969).

    CAS  Google Scholar 

  89. SOBRERO, A., MCLEOD, J.: An immediate post-coital test. Fert. Steril. 13, 184 (1962).

    CAS  Google Scholar 

  90. SPEISER, P.: Über die bisher jüngste menschliche Frucht (27 mm/2.2 g) an der bereits die Erbmerkmale Al, M, N, s, Fy (a+), C, c, D, E, e, Jk (a+?) im Blut festgestellt werden konnten. Wien. klin. Wschr. 71, 549 (1959).

    PubMed  CAS  Google Scholar 

  91. STEFFEN, C.: Allgemeine und experimentelle Immunologic und Immunpathologie. Stuttgart: Georg Thieme 1968.

    Google Scholar 

  92. STRAUSS, F.: Personal communication.

    Google Scholar 

  93. SZULMAN, A. E.: The histological distribution of blood group substances in man as disclosed by immunofluorescence. The A, B, and H antigens in embryos and fetuses from 18 mm in length. J. exp. Med. 119, 503 (1964).

    Article  PubMed  CAS  Google Scholar 

  94. SZULMAN, A. E.: The ABH antigens in human tissues and secretions during embryonal development. J. Histochem. Cytochem. 13, 752 (1965).

    Article  PubMed  CAS  Google Scholar 

  95. VEIT, J.: Über Deportation von Chorionzotten. (Verschleppung von Zotten in mütterliche Blutbahnen.) Z. Geburtsh. Gynäk. 44, 466 (1901).

    Google Scholar 

  96. VOLKOVA, L. S., MAYSKY, I. N.: Immunological interaction between mother and embryo. In: EDWARDS, R. G.: Immunology and reproduction, p. 211. Hertford: Stephen Austin and Sons Ltd. 1969.

    Google Scholar 

  97. WILKEN, H.: Der Antigencharakter der Plazenta. Z. ärztl. Fortb. 23, 1290 (1962).

    Google Scholar 

  98. WILKEN, H.: Über den Nachweis von Gewebs-Antikörpern gegen Plazenta, Leber und Niere in der Schwangerschaft. Z. Geburtsh. Gynäk. 161, 113 (1963).

    CAS  Google Scholar 

  99. WILSON, L.: Spermagglutinins in human semen and blood. Proc. Soc. exp. Biol. (N. Y.) 85, 652 (1954).

    CAS  Google Scholar 

  100. WOODRUFF, M. F. A.: Transplantation immunity and immunological problem of pregnancy. Proc. roy. Soc. London 148, 68 (1958).

    Article  CAS  Google Scholar 

  101. ZIMMER, F., PARKS, J.: Die Schwangerschaft als immunologisches Problem. Fortschr. Med. 85, 1013 (1967).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1970 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Krieg, H. (1970). Immunology of Reproduction. In: Gibian, H., Plotz, E.J. (eds) Mammalian Reproduction. Colloquium der Gesellschaft für Biologische Chemie in 9.–11. April 1970 in Mosbach/Baden, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-64993-6_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-64993-6_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64995-0

  • Online ISBN: 978-3-642-64993-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics