Advertisement

Abstract

The ovum is fertilized in the oviduct, and during the first days of pregnancy the oviduct is the physiological home of the early embryo. Also, remarkably enough, the oviduct is capable of trans-porting the male and female germ cells in opposite directions at practically the same time. It is only in the last few years that we have come to recognise clearly the complex function of this organ in instituting and regulating the earliest phases of pregnancy and, as a result of this knowledge, we are now in a better position to explain the causes of certain cases of sterility and infertility in women, and also to understand some peripheral mechanisms of action of hormonal contraceptives.

Keywords

Fallopian Tube Corpus Luteum Ciliated Cell Tubal Lumen Ciliary Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. ADAMS, C. E.: A study of fertilization in the rabbit: The effect of postcoital ligation of the Fallopian tube or uterine horn. J. Endocr. 13, 296 (1956).PubMedGoogle Scholar
  2. ADAMS, C. E.: Egg development in the rabbit: The influence of postcoital ligation of the uterine tube and of ovariectomy. J. Endocr. 16, 283 (1958).PubMedGoogle Scholar
  3. ALDEN, R. H.: The periovarial sac in the albino rat. Anat. Rec. 83, 421 (1942a).Google Scholar
  4. ALDEN, R. H.: The oviduct and egg transport in albino rat. Anat. Rec. 84, 137 (1942b).Google Scholar
  5. ALDEN, R. H.: Aspects of the egg-ovary-oviduct relationship in the albino rat. I. Egg passage and development following ovariectomy. J. exp. Zool. 90, 159 (1942c).Google Scholar
  6. ALLEN, W. M., CORNER, G. W.: Physiology of the corpus luteum. III. Normal growth and implantation of embryos after early ablation of the ovaries under the influence of extracts of corpus luteum. Amer. J. Physiol. 88, 340 (1929).Google Scholar
  7. ANDERES, E.: Zur Frage des Eitransportes durch die Tube. Schweiz. med. Wschr. 71, 364 (1941).Google Scholar
  8. ANDERSEN, D. H.: The rate of passage of the mammalian ovum trough the various portions of the Follopian tube. Amer. J. Physiol. 82, 552 (1927).Google Scholar
  9. ANDERSEN, D. H.: Comparative anatomy of the tubo-uterine junction. Amer. J. Anat. 42, 255 (1928).Google Scholar
  10. AUSTIN, C. R., BRADEN, A. W. H.: Passage of the sperm and the penetration of the egg in mammals. Nature (Lond.) 170, 919 (1952).Google Scholar
  11. AVERILL, R. L. W., ROWSON, L. E. A.: Ovum transfer in sheep. J. Endocr. 16, 326 (1958).PubMedGoogle Scholar
  12. BEATTY, R. A.: Transplantation of mouse eggs. Nature (Lond.) 168, 995 (1951).Google Scholar
  13. BENNET, J. P.: The effect of drugs on egg transport. Advances in the Biociences 4 (1970). Oxford-London-Edinburgh-New York-Toronto-Sidney- Paris-Braunschweig: Pergamon Press-Vieweg.Google Scholar
  14. BISHOP, D. W.: The tubal secretions of the rabbit oviduct. Anat. Rec. 125, 125 (1956a).Google Scholar
  15. BISHOP, D. W.: Oxygen concentrations in the rabbit genital tract. Proc. III. Internat. Congr. on Animal Reproduction Cambridge, Engl., June 1956b, Sect. I.Google Scholar
  16. BISHOP, D. W.: Active secretion in the rabbit oviduct. Amer. J. Physiol. 187, 347 (1956c).PubMedGoogle Scholar
  17. BJÖRK, L.: Cineradiographic studies on the Fallopian tube in rabbits. Acta radiol. Suppl. 176 (1959).Google Scholar
  18. BLACK, D. L., ASDELL, S. A.: Transport through the rabbit oviduct. Amer. J. Physiol. 192, 63 (1958).PubMedGoogle Scholar
  19. BLACK, D. L., ASDELL, S. A.: Mechanism controlling entry of ova into rabbit uterus. Amer. J. Physiol. 197, 1275 (1959).PubMedGoogle Scholar
  20. BLACK, D. L., ASDELL, S. A., DAVIS, J.: A blocking mechanism in the cow oviduct. J. Reprod. Fertil. 4, 21 (1962).PubMedGoogle Scholar
  21. BLACK, D. L., ASDELL, S. A., DUBY, R. T., RIESEN, J.: Apparatus for the continuous collection of sheep oviduct fluid. J. Reprod. Fertil. 6, 257 (1963).PubMedGoogle Scholar
  22. BORELL, U., NILSSON, O., WESTMAN, A.: Ciliary activity in the rabbit Fallopian tube during estrus and after copulation. Acta obstet. gynec. scand. 36, 22 (1957).PubMedGoogle Scholar
  23. BRADEN, A. W. H., AUSTIN, C. R.: The number of sperms about the eggs in mammals and its significance for normal fertilization. Aust. J. biol. Sci. 7, 543 (1954).PubMedGoogle Scholar
  24. BURDICK, H. O., PINCUS, G.: The effect of oestrin injection upon the developing ova of mice. Amer. J. Physiol. 111, 201 (1935).Google Scholar
  25. CAFFIER, P.: Studien zum Eitransport beim Menschen. I. Mitteilung: Der Eiabnahmemechanismus. Zbl. Gynäk. 60, 1873 (1936).Google Scholar
  26. CHANG, M. C.: Probability of normal development after transplantation of fertilized rabbit ova stored at different temperatures. Proc. Soc. exp. Biol. (N.Y.) 68, 680 (1948).Google Scholar
  27. CHANG, M. C.: Fertility and sterility as revealed in the study of fertilization and development of rabbit eggs. Fertil. Steril. 2, 205 (1951a).PubMedGoogle Scholar
  28. CHANG, M. C.: Fertilization in relation to the number of spermatozoa in the Fallopian tubes of rabbits. Ann. Ostet. Ginec. 73, 918 (1951b).PubMedGoogle Scholar
  29. CHANG, M. C.: Fertilization and normal development of follicular oocytes in the rabbit. Science 121, 867 (1955).PubMedGoogle Scholar
  30. CHANG, M. C.: Effects of certain antifertility agents on the development of rabbit ova. Fertil. Steril. 15, 97 (1964).PubMedGoogle Scholar
  31. CHANG, M. C., YANAGAMACHI, R.: Effect of estrogens and other compounds as oral antifertility agents on the development of rabbit ova and hamster embryos. Fertil. Steril. 16, 281 (1965).PubMedGoogle Scholar
  32. CLEWE, T. H., MASTRIANNI, L.: Mechanism of ovum pickup. I. Functional capacity of rabbit oviducts ligated near the fimbria. Fertil. Steril. 9, 13 (1958).PubMedGoogle Scholar
  33. DEANESLY, R.: Further observations on the effect of oestradiol on tubal eggs and implantation in the guinea pig. J. Reprod. Fertil. 5, 49 (1963).PubMedGoogle Scholar
  34. DOWLING, D. F.: Problems of the transplantation of fertilized ova. J. agric. Sci. 39, 374 (1949).Google Scholar
  35. DOYLE, L. L., GATES, A. H., NOYES, R. W.: Asynchronous transfer of mouse ova. Fertil. Steril. 14, 215 (1963).Google Scholar
  36. DUBREUIL, G.: Le réseau lymphatique fonctionnel des franges et des plis de la trompe, son rôle dans la captation et le cheminement de l’oeuf chez la femme. Gynéc. et Obstet. 44, 397 (1944).Google Scholar
  37. DYROFF, R.: Der Mechanismus der Eiabnahme beim Menschen und seine Störungen. Zbl. Gynäk. 56, 2987 (1932).Google Scholar
  38. EDGAR, D. G., ASDELL, S. A.: The valve like action of the utero-tubal junction of the ewe. J. Endocr. 21, 315 (1960).PubMedGoogle Scholar
  39. ELERT, R.: Der Mechanismus der Eiabnahme im Laparoskop. Zbl. Gynäk. 69, 38 (1947).Google Scholar
  40. ELGER, W.: Einfluß von Gestagenen auf Befruchtung, Eiernährung, Eitransport und Schwangerschaftsverlauf. Handbuch der experimentellen Pharmakologie, Band XXII/2. Berlin-Heidelberg-New York: Springer 1969.Google Scholar
  41. ERB, H.: Zur hormonalen Regulation der Tubenmotilität. Basel-New York: S. Karger 1969.Google Scholar
  42. FAWCETT, D. W., PORTER, K. R.: A study of fine structure of ciliated epithelia. J. Morph. 94, 221 (1954).Google Scholar
  43. FRIZ, M., MEY, R.: Die Bedeutung der Eileitersekrete fur die Physiologie der Fortpflanzung. Geburtsh. Frauenheilk. 19, 706 (1959).PubMedGoogle Scholar
  44. GREENWALD, G. S.: Interruption of pregnancy in the rabbit by the administration of estrogen. J. exp. Zool. 135, 461 (1957).PubMedGoogle Scholar
  45. GREENWALD, G. S.: The comperative effectiveness of estrogens in interrupting pregnancy in the rabbit. Fertil. Steril. 10, 155 (1959).PubMedGoogle Scholar
  46. GREENWALD, G. S.: Tubal transport of ova in the rabbit. Anat. Rec. 133, 386 (1959).Google Scholar
  47. GREENWALD, G. S.: A study of the transport of ova through the rabbit oviduct. Fertil. Steril. 12, 80 (1961).PubMedGoogle Scholar
  48. GREENWALD, G. S.: In vivo recording of intramural pressure changes in the rabbit oviduct. Fertil. Steril. 14, 666 (1963).PubMedGoogle Scholar
  49. GREENWALD, G. S.: Interruption of early pregnancy in the rabbit by a single injection of oestradiolcyclopentyl-proprionate. J. Endocr. 26, 133 (1963).PubMedGoogle Scholar
  50. GREGORY, P. W.: The early embryology of the rabbit. Contr. Embryol. Carneg. Inst. 21, 141 (1930).Google Scholar
  51. HAFEZ, E. S. E.: Tubo-ovarian mechanism and ova reception in mammals. Cornell Vet. 49, 459 (1959).PubMedGoogle Scholar
  52. HAFEZ, E. S. E.: Procedures and problems of manipulation, selection, storage, and transfer of mammalian ova. Cornell Vet. 6, 299 (1961).Google Scholar
  53. HAFEZ, E. S. E.: In vivo and in vitro studies on rabbit ova; non-surgical ova transfer as a target. Proc. IVth Intern. Congr. Animal Reprod. The Hague 1961.Google Scholar
  54. HAFEZ, E. S. E.: Endocrine control of reception, transport, development and loss of rabbit ova. J. Reprod. Fertil. 3, 14 (1962).PubMedGoogle Scholar
  55. HAFEZ, E. S. E.: Pressure fluctuations during uterotubal kymographic insufflation in pregnant rabbits. Fertil. Steril. 13, 426 (1962).PubMedGoogle Scholar
  56. HAFEZ, E. S. E.: The uterotubal junction and the luminal fluid of the uterine tube in the rabbit. Anat. Rec. 145, 7 (1963).PubMedGoogle Scholar
  57. HARPER, M. J. K.: The mechanism involved in the movement of newly ovulated eggs through the ampulla of the rabbit Fallopian tube. J. Reprod. Fertil. 2, 522 (1961).Google Scholar
  58. HARPER, M. J. K.: The effects of constant doses of oestrogen and progesterose on the transport of artificial eggs through the reproductive tract of ovariectomized rabbits. J. Endocr. 30, 1 (1964).PubMedGoogle Scholar
  59. HARPER, M. J. K., BENNET, J. P., BOURSNELL, J. C., ROWSON, L. E. A.: An autoradiographic method for the study of egg transport in the rabbit Fallopian tube. J. Reprod. Fertil. 1, 249 (1960).Google Scholar
  60. HARTMAN, C. G.: Ovulation, fertilization and the transport and viability of eggs and spermatozoa. In: Sex and Internal Secretions, ed. E. ALLEN. Baltimore: Williams & Wilkins Comp. 1939.Google Scholar
  61. HASELHORST, G.: Weibliche Sterilität. Arch. Gynäk. 161, 81 (1936).Google Scholar
  62. HORSTMANN, E.: Über die Bedeutung der Epoophoronmuskulatur. Arch. Gynak. 182, 314 (1952).Google Scholar
  63. HUMPHREY, K. W.: Mechanisms involved in egg transport. In: Advances in the Biosciences, Vol. 4. Oxford-London-Edinburgh-New York-Toronto- Sidney-Paris-Braunschweig: Pergamon Press-Vieweg 1970.Google Scholar
  64. HUNTER, G. L., ADAMS, C. E., ROWSON, L. E. A.: Inter-breed ovum transfer in sheep. J. Agric. Sci. 46, 143 (1955).Google Scholar
  65. KING, J. L., COLLINS, M., PETERSON, H. E.: Experimental interference with rabbit embryos in the early stages of their development. Amer. J. Physiol. 102, 375 (1932).Google Scholar
  66. KIPFER, K.: Die Muskulatur der Tuba uterina als funktionelles System. Acta Anat. 9, 35 (1950).PubMedGoogle Scholar
  67. KNEER, M.: Anatomie und Funktion der Muskulatur des menschlichen Eileiters. Arch. Gynäk. 176, 156 (1948/49).Google Scholar
  68. KNEER, M., CLESS, H.: Flimmerung und Strömung im menschlichen Eileiter. Geburtsh. Frauenheilk. 11, 233 (1951).PubMedGoogle Scholar
  69. KOESTER, H.: Tierexperimentelle Untersuchungen zur Physiologie der Eileitersekretion während der Zeit der Eipassage. Bibl. Gynaecologica (Basel) (im Druck).Google Scholar
  70. KOK, F.: Bewegung des muskulosen Rohres der Fallopischen Tube. Arch. Gynäk. 127, 384 (1926).Google Scholar
  71. LEE, F. C.: The tubo-uterine junction of various mammals. Johns Hopk. Hosp. Bull. 42, 335 (1928).Google Scholar
  72. LEONARD, S. L., FERLMAN, P. L.: Conditions affecting the passage of spermatozoa through the utero-tubal junction of the rat. Anat. Rec. 104, 89 (1949).PubMedGoogle Scholar
  73. MARTIUS, H.: Grundlagen der Gynäkologie. Stuttgart: Thieme 1950.Google Scholar
  74. MASTROIANNI, L., BEER, F., SHAH, U., CLEWE, T. H.: Endocrine regulations of oviduct secretions in the rabbit. Endocrinology 68, 92 (1961).PubMedGoogle Scholar
  75. MASTROIANNI, L., EHTESHAMZADEH, J.: Corona cell dispersing properties of rabbit tubal fluid. J. Reprod. Fertil. 8, 145 (1964).PubMedGoogle Scholar
  76. MASTROIANNI, L., SHAH, U., ABDTJL-KARIM, R.: Prolonged volumetric collection of oviduct fluid in the rhesus monkey. Fertil. Steril. 12, 417 (1961).Google Scholar
  77. MASTROIANNI, L., WALLACH, R. C.: Effect of ovulation and early gestation on the oviduct secretion in the rabbit. Amer. J. Physiol. 200, 815 (1961).Google Scholar
  78. MCCLEAN, D., ROWLANDS, I. W.: The role of hyaluronidase in fertilization. Nature (Lond.) 150, 627 (1942).Google Scholar
  79. MCLAREN, A., MICHIE, A. D.: Studies on the transfer of fertilized mouse eggs to uterine foster mothers. J. exp. Biol. 33, 394 (1956).Google Scholar
  80. MIKULICZ-RADECKI, F. VON: Experimentelle Untersuchungen über Tubenbewegungen. Arch. Gynäk. 128, 318 (1926).Google Scholar
  81. MIKULICZ-RADECKI, F. VON: Diskussionsbemerkung zu WESTMANN: Studien über den Bewegungsmechanismus des Eileiters.Google Scholar
  82. MIKULICZ-RADECKI, F. VON: Der Eiauffangmechanismus bei der Frau und seine Bedeutung für die Sterilität. Schriften der Königsberger gelehrten Gesellschaft 13 (1937), Heft 6. Halle (Saale): Max Niemeyer.Google Scholar
  83. NOYES, R. W., ADAMS, C. E., WALTON, A.: The transport of ova in relation to the dosage of oestrogen in ovariectomized rabbits. J. Endocr. 18, 108 (1959).PubMedGoogle Scholar
  84. NOYES, R. W., ADAMS, C. E., WALTON, A.: The passage of spermatozoa through the genital tract of female rabbits after ovariectomy and oestrogen treatment. J. Endocr. 18, 165 (1959).PubMedGoogle Scholar
  85. NOYES, R. W., DICKMANN, Z.: Relationship of ovular age ot endometrial development. J. Reprod. Fertil. 1, 186 (1960).Google Scholar
  86. NOYES, R. W., DICKMANN, Z.: Survival of ova transferred into the oviduct of the rat. Fertil. Steril. 12, 67 (1961).PubMedGoogle Scholar
  87. PARKER, G. H.: The passage of sperma and eggs through the oviduct in terrestrial vertebrates, Phil. Trans. Roy. Soc. B 219, 381 (1931).Google Scholar
  88. PINCUS, G., KIRSCH, R. E.: The sterility in rabbits produced by injections of oestrone and related compounds. Amer. J. Physiol. 115, 219 (1936).Google Scholar
  89. PINCUS, G., WERTHESSEN, N. T.: The sterility in rabbits produced by injections of oestrone and related compounds. Amer. J. Physiol. 115, 219 (1938).Google Scholar
  90. RAUSCHER, H.: Discussion remark. Arch. Gynäk. 207, 181 (1969).Google Scholar
  91. ROBINSON, T. J.: Reproduction in the ewe. Biol. Rev. 26, 121 (1951).Google Scholar
  92. ROCKER, I.: The anatomy of the utero-tubal junction area. Proc. roy. Soc. Med. 57, 707 (1964).Google Scholar
  93. SCHRÖDER, R.: Der Eileiter: In: Handbuch der mikroskopischen Anatomie des Menschen, von v. MÖLLENDORF, Bd. VII, Teil 1. Berlin: Springer 1930.Google Scholar
  94. SECKINGER, D.: Spontaneous contractions of the Fallopian tube of the domestic pig with reference to the oestrous cycle. Johns Hopk. Hosp. Bull. 34, 236 (1923).Google Scholar
  95. SECKINGER, D., CORNER, G.: Cyclic variations on the spontaneous contractions of the Fallopian tube of the macacus rhesus. Anat. Rec. 26, 299 (1923).Google Scholar
  96. SECKINGER, D., SYNDER, F. F.: Cyclic variations in the spontaneous contractions of the human Fallopian tube. Proc. Soc. exp. Biol. (N.Y.) 21, 519 (1924).Google Scholar
  97. SECKINGER, D., SYNDER, F. F.: Cyclic changes in the spontaneous contractions of the human Fallopian tube. Johns Hopk. Hosp. Bull. 39, 371 (1926).Google Scholar
  98. SIEGLER, S. L.: Fertility in women. Philadelphia: Lippincott 1944.Google Scholar
  99. SQUIER, R.: The living egg and early stages of its development in the Guinea pig. Contrib. Embryol. Carneg. Instn 21, 223 (1932).Google Scholar
  100. STANGE, H. H.: Vergleichende morphologische Untersuchungen an der menschlichen Tube in extremen Funktionszuständen zur Klärung der Frage: „Gibt es einen Sphincter infundibuli?“Zbl. Gynäk. 74, 1176 (1952).Google Scholar
  101. STANGE, H. H.: Zur funktionellen Morphologie des Fimbrienendes der menschlichen Tube und des Epoophoron. Arch. Gynäk. 182, 77 (1952).Google Scholar
  102. STEGNER, H. E.: Elektronenmikroskopische Untersuchungen über die Sekretionsmorphologie des menschlichen Tubenepithels. Arch. Gynäk. 197, 351 (1962).Google Scholar
  103. SWYER, G. I. M.: A tubal factor concerned in the denudation of rabbit ova. Nature (Lond.) 159, 873 (1947).Google Scholar
  104. WALTON, A., HAMMOND, J.: Observations on ovulation in the rabbit. Brit. J. exp. Biol. 6, 190 (1928).Google Scholar
  105. WESTMAN, A.: A contribution to the question of the transit of the ovum from ovary to uterus in rabbits. Acta obstet. gynec. scand. 25, 475 (1926).Google Scholar
  106. WESTMAN, A.: Studien über den Bewegungsmechanismus der Eileiter. Z. Geburtsh. Gynak. 95, 189 (1929).Google Scholar
  107. WESTMAN, A.: Investigations into the transit of ova in man. J. Obstet. Gynec. Brit. Emp. 44, 821 (1937).Google Scholar
  108. WIMSATT, W. A., WALDO, C. M.: The normal occurence of a peritoneal opening in the bursa ovarii of the mouse. Anat. Rec. 93, 74 (1945).Google Scholar
  109. WIMPFHEIMER, S., FERESTEN, M.: The effect of castration in tubal contraction of the rabbit as determined by the Rubin test. Endocrinology 25, 91 (1939).Google Scholar
  110. WINTENBERGER, S.: Recherches sur les relation entre l’oeuf et le tractus maternel chez les mammiféres. Etudes de la traversé de l’oviducte par l’oeuf fécondé de brebis. Ann. Zootech. 2, 269 (1953).Google Scholar
  111. WINTENBERGER-TORRÉS, S.: Mouvements des trompes et progression des oeufs chez la brebis. Ann. Biol. anim. 1, 121 (1961).Google Scholar
  112. WISLOCKI, G. B., GUTTMACHER, A. F.: Spontaneous persitalsis of the excised whole uterus and Fallopian tubes of the sow with reference to the ovulation cycle. Johns Hopk. Hosp. Bull. 35, 246 (1924).Google Scholar
  113. WISLOCKI, G. B., GUTTMACHER, A. F., SYNDER, F. F.: The experimental acceleration of the rate of transport of ova through the Fallopian tube. Johns Hopk. Hosp. Bull. 52, 379 (1933).Google Scholar
  114. WU, D. H., ALLEN, W. M.: Maintenance of pregnancy in castrated rabbits by 17-alpha-hydroxy-progesterone and by progesterone. Fertil. Steril. 10, 439 (1959).PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1970

Authors and Affiliations

  • H. Koester
    • 1
  1. 1.Universitäts-FrauenklinikGießenGermany

Personalised recommendations