Noradrenergic and Dopaminergic Influences on Thirst
Two opposing roles have been proposed for central adrenergic neurones in the control of drinking, facilitatory and inhibitory. Although neither role has been established firmly, experimental evidence exists in support of each. Various pharmacological alterations of adrenergic function and different experimental conditions tend to differentially emphasize one or the other role.
KeywordsWater Intake Water Deprivation Preoptic Area Ingestive Behaviour Brain Catecholamine
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- COSTA, E., SPANO, P.F., GROPPETTI, A., ALGERI, S. NEFF, N.: Simultaneous determination of tryptophan, tyrosine, catecholamine and serotonin specific activity in rat brain. Atti. Accad. Med. Lombarda 23, 1100–1104 (1968).Google Scholar
- SETLER, P. E.: The role of catecholamines in thirst. In: Neuropsychology of thirst (Eds. A. N. EPSTEIN, H. R. KISSILEFF, E. STELLAR), pp. 279–291. Washington, D.C.: Winston and Sons 1973.Google Scholar
- SMITH, G. P.: Introduction to neuropharmacology of thirst. In: Neuropsychology of thirst (Eds. A. N. EPSTEIN, H. R. KISSILEFF, and E. STELLAR), pp. 231–241. Washington, D.C.: V. H. Winston and Sons 1973.Google Scholar
- THOENEN, H., TRANZER, J. P.: Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 261, 271–288 (1968).Google Scholar
- Ungerstedt, U.: Postsynaptic supersensitivity after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system. Acta physiol. Scand. Suppl. 367, 69–95 (1971a).Google Scholar
- ——— Adipsia and aphagia after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system. Acta physiol. Scand. Suppl. 367, 95–122 (1971b).Google Scholar