The Rejection Response to Segmental Grafts of the Femoral Artery in Inbred Rat Strains
The femoral artery represents a peripheric vessel with a relatively high percentage of muscle cells in its wall compared with the aorta. The rejection of aortic segmental grafts has been described extensively by Thiede in 1977. He found the strength of the rejection process and a consecutive formation of aneurysms to be correlated with the histocompatibility between donor and recipient. In this study, we wanted to describe the microscopic pattern of the rejection process of segments of the femoral artery and the functional alterations such as thrombosis or aneurysms of these grafts in dependence on the immunogenetic difference between donor and recipient.
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- Thiede A (1977) Gefäßtransplantation. Die Bedeutung immunoligischer Reaktionsmechanismen. Untersuchungen an standardisierten Ratteninzuchtkombinationen. Schattauer, Stuttgart ( Ergebnisses der Angiologie, Vol 15Google Scholar