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Technique for Orthotopic Rat Liver Transplantation

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Abstract

After the introduction of microvascular suture techniques by Lee and Fisher in 1961, it took more than a decade of microsurgical pioneer work before a technique for orthotopic rat liver transplantation could be presented (Lee et al. 1973). This technique, however, required a portosystemic shunt and was a difficult operation. To my knowledge, nobody, except its inventors, was able to reproduce the results.

This work was supported by the Deutsche Forschungsgemeinschaft SFB 111/B9

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References

  • Engemann R, Thiede A, Lee S (1979) Syngeneic orthotopic total replacement of the liver in rats. Post operative function control using angiography and transaminase courses. Excerpta Medica Int Congr Ser 465:402–405

    Google Scholar 

  • Hansen HH, Kim Y, Lie TS (1979) Orthotopic liver transplantation in the rat - special reference to arterialization. Excerpta Medica Int Congr Ser 465:394–397

    Google Scholar 

  • Hess F, Jerusalem C, Heyde N (1972) Advantages of auxiliary liver homotransplantations in the rat. Arch Surg 104:76–80

    PubMed  CAS  Google Scholar 

  • Houssin D, Gigou M, Franco D, Szekely AM, Bismith H (1979) Spontaneous long-term survival of liver allografts in inbred rats. Transplant Proc 11:567–570

    PubMed  CAS  Google Scholar 

  • Kamada N, Calne RY (1979) Orthotopic liver transplantation in the rat: technique using cuff for portal vein anastomosis and biliary drainage. Transplantation 28:49–50

    Article  Google Scholar 

  • Kamada N, Davies HS, Wight P, Culank L, Roser B (1983) Liver transplantation in the rat. Biochemical and histological evidence of complete tolerance induction in non-rejection strains. Transplantation 35:304–311

    Article  PubMed  CAS  Google Scholar 

  • Lee S, Edgington TS (1966) Liver transplantation in the rat. Surg Forum 17:220–222

    PubMed  CAS  Google Scholar 

  • Lee S, Fisher B (1961) Portocaval shunt in the rat. Surgery 50:668–672

    PubMed  CAS  Google Scholar 

  • Lee S, Charters AC III, Chandler JG, Orloff MJ (1973) A technique for orthotopic liver transplantation in the rat. Transplantation 16:664–669

    Article  PubMed  CAS  Google Scholar 

  • Lee S, Charters AC III, Orloff MJ (1975) Simplified technique for orthotopic liver transplantation in the rat. Am J Surg 130:38–40

    Article  PubMed  CAS  Google Scholar 

  • Lie TS, Hansen HH, Niehaus KJ (1983) Bedeutung der Arterialisation des Transplantates bei Rattenlebertransplantation. Langenbecks Arch Chir 359:133–142

    Article  PubMed  CAS  Google Scholar 

  • Limmer J, Herbertson BM, Calne RY (1980) Orthotopic rat liver transplantation using different combinations of four inbred strains. Eur Surg Res 12:343–348

    Article  PubMed  CAS  Google Scholar 

  • Zimmermann F, Butcher GW, Davies HS, Brons G, Kamada N, Tiirel O (1979) Techniques for orthotopic liver transplantation in the rat and some studies of the immunologic responses to fully allogeneic liver grafts. Transplant Proc 11:571–577

    PubMed  CAS  Google Scholar 

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© 1985 Springer-Verlag Berlin, Heidelberg

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Engemann, R. (1985). Technique for Orthotopic Rat Liver Transplantation. In: Thiede, A., Deltz, E., Engemann, R., Hamelmann, H. (eds) Microsurgical Models in Rats for Transplantation Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61657-0_12

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  • DOI: https://doi.org/10.1007/978-3-642-61657-0_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64899-1

  • Online ISBN: 978-3-642-61657-0

  • eBook Packages: Springer Book Archive

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