History and Development of Experimental Microsurgery in Rats

Conference paper


Shortly after the end of World War II, most American universities were equipped with dog laboratory facilities where vascular surgeries were tested to develop open heart surgery and kidney transplantation techniques. The University of Pittsburgh was no exception. When I completed general surgical residency at St. Francis Hospital in Pittsburgh in 1955, I was invited to join the surgical research team conducted by Dr. Bernard Fisher, Surgical Research Division of the Department of Surgery, University of Pittsburgh. At that time, surgical physiological observation of hypothermia, portacaval shunt, and vascular reconstruction was highlighted, employing the dog and skin graft experiment in the rat. At that period, rats were seldom used in surgical laboratories despite a long history of rat usage in allied biological research.


Renal Transplantation Kidney Transplantation Pancreas Transplantation Portacaval Shunt Transplantation Immunology 
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© Springer-Verlag Berlin, Heidelberg 1985

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  • Sun Lee

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