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Bioaccumulation and Biomagnification of Hydrophobic Persistent Compounds as Exemplified by Hexachlorobenzene

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Chemicals in the Aquatic Environment

Part of the book series: Springer Series on Environmental Management ((SSEM))

Summary

Information reflecting the present state of knowledge about bioaccumulation of hexachlorobenzene (HCB) and other hydrophobic organochlorines has been compiled. In this critical review, some possible pitfalls in the interpretation of experimental results and field data on bioaccumulation are pointed out. Starting from “the fugacity model” approach, some new hypotheses are presented on the relationship between bioaccumulation and different abiotic and biotic factors. Among the processes discussed, special attention has been given to the uptake of xenobiotics with food. A better understanding of the mechanisms of nutrient absorption in the gut seems to be crucial in this context. Furthermore, biomagnification or food chain transfer resulting in an increase in concentration with trophic level is considered. It is concluded that although biomagnification of some organochlorines may be detected in the aquatic environment, the phenomenon has a low magnitude unless the airbreathing aquatic animals are included in the analysis.

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References

  • Addison RF (1982) Organochlorine compounds and marine lipids. Prog Lipid Res 21: 47–71

    Article  PubMed  CAS  Google Scholar 

  • Anliker R, Clarke EA, Moser P (1981) Use of the partition coefficient as an indicator of bioaccumulation tendency of dyestuffs in fish. Chemosphere 10: 263–274

    Article  CAS  Google Scholar 

  • Bjerk JE, Brevik EM (1980) Organochlorine compounds in aquatic environments. Arch Environ Contamin Toxicol 9: 743–750

    Article  CAS  Google Scholar 

  • Bobyleva NV, Belyalva AN (1982) Genesis and composition of lipids from the suspended matter and bottom sediments of the Baltic Sea. Okeanologiya 22: 757–763 (in Russian)

    CAS  Google Scholar 

  • Bruggeman WA (1982) Hydrophobic interactions in the aquatic environment. In: Hutzinger O (ed) Handbook of environmental chemistry. Springer, Berlin Heidelberg, vol 2 pt B. pp 29–49

    Google Scholar 

  • Bruggeman WA, Opperhuizen A, Wijbenga A, Hutzinger O (1984) Bioaccumulation of super-lipophilic chemicals in fish. Toxicol Environ Chem 7:173–189

    Article  CAS  Google Scholar 

  • Carlberg GE, Martinsen K, Kringstad A, Gjessing E, Grande M, Källqvist T, Skåre JV (1985) Investigation of the influence of aquatic humus on the bioavailability of chlorinated micro- pollutants toward fish. In: Bjørseth A, Angeletti G (eds) Organic micropollutants in the aquatic environment. Proc 4th Eur Symp, Vienna, Austria, Oct 22–24,1985

    Google Scholar 

  • Caron G, Suffet IH, Belton T (1985) Effect of dissolved organic carbon on the environmental distribution of nonpolar organic compounds. Chemosphere 14: 993–1000

    Article  CAS  Google Scholar 

  • Clark T, Clark K, Paterson S, MacKay D (1988) Wild life monitoring, modeling and fugacity.Environ Sci Technol 22:120–127

    CAS  Google Scholar 

  • Coates M, Chapman HF, Cowell DW (1984) Effects of grazing by deposit-feeders on biogenic hydrocarbons in coral-reef surface sediments. Mar Biol 81: 87–95

    Article  CAS  Google Scholar 

  • Connolly JP, Pedersen CJ (1988) A thermodynamic-based evaluation of organic chemical accumulation in aquatic organisms. Environ Sci Technol 22: 99–103

    Article  CAS  Google Scholar 

  • Courtney WAM, Langston WJ (1980) Accumulation of polychlorinated biphenyls in turbot (Scophthalmus maximus) from seawater sediments and food. Helgoländer Meeresunters 33: 301- 312

    Article  Google Scholar 

  • Cowey CB, Sargent JR (1979) Nutrition. In: Hoar WS, Randall DJ, Brett JR (eds) Fish physiology, vol 8. Academic Press, New York London, pp 1–69

    Google Scholar 

  • Dobbs AJ, Williams, N (1983) Fat solubility - a property of environmental relevance? Chemosphere 12: 97–104

    Article  CAS  Google Scholar 

  • Duinker JC, Hillebrand MTJ, Boon, JP (1983) Organochlorines in benthic invertebrates and sediments from the Dutch Wadden Sea; identification of individual PCB components. Neth J Sea Res 15 (2): 141–169

    Article  Google Scholar 

  • Ekelund R, Granmo Å, Berggren M, Renberg L, Wahlberg C (1987) Influence of suspended solids on bioavailability of hexachlorobenzene and lindane to the deposit-feeding bivalve Abra nitida (Müller). Bull Environ Contamin Toxicol 38: 500–508

    Article  CAS  Google Scholar 

  • Ernst, W (1977) Determination of the bioconcentration potential of marine organisms - a steady state approach I Bioconcentration data for seven chlorinated pesticides in mussels (Mytilus edulis) and their relation to solubility data. Chemosphere 11: 731–740

    Article  Google Scholar 

  • Ernst W (1980) Effects of pesticides and related organic compounds in the sea. Helgoländer Meeresunters 33: 301–312

    Article  Google Scholar 

  • Ernst W (1985) Hexachlorobenzene (HCB) in the marine environment. Distribution, fate and toxicological aspects. Hexachlorobenzene. Proc Int Symp. IARC Sci Publ 77. Oxford Univ Press

    Google Scholar 

  • Falandysz J (1982) Chlorinated hydrocarbons in salmon netted in Gdansk Bay, Baltic Sea (Poland). Meeresforschung 29: 219–224

    CAS  Google Scholar 

  • Flynn GL, Yalkowsky SH (1972) Correlation and prediction of mass transport across membranes I: Influence of alkyl chain length on flux-determining properties of barrier and diffusant. J Pharm Sci 61: 838–852

    Article  PubMed  CAS  Google Scholar 

  • Fowler SW, Villeneuve JP, Burns KA (1985) Vertical flux of hexachlorobenzene (HCB) in coastal waters of the northwest Mediterranean Sea. Hexachlorobenzene. Proc Int Symp. IARC Sci Publ 77. Oxford Univ Press

    Google Scholar 

  • Geyer H, Sheehan P, Kotzias D, Freitag D, Korte F (1982) Prediction of ecotoxicological behaviour of chemicals: relationship between physico-chemical properties and bioaccumulation of organic chemicals in the mussel Mytilus edulis. Chemosphere 11:1121–1134

    Article  CAS  Google Scholar 

  • Geyer H, Politzki G, Freitag D (1984) Prediction of ecotoxicological behaviour of chemicals: relationship between n-octanol/water partition coefficient and bioaccumulation of organic chemicals by alga Chlorella. Chemosphere 13: 269–284

    Article  CAS  Google Scholar 

  • Goerke H, Eder G, Weber K, Ernst W (1979) Patterns of organochlorine residues in animals of different trophic levels from the Weser esturary. Mar Pollut Bull 10:127–133

    Article  CAS  Google Scholar 

  • Gossett RW, Brown DA, Young DR (1983) Predicting the bioaccumulation of organic compounds in marine organisms using octanol/water partition coefficients. Mar Pollut Bull 14 (10): 387–392

    Article  CAS  Google Scholar 

  • Griesbach S, Peters RH, Youakim S (1982) An allometric model for pesticide bioaccumulation. Can J Fish Aquat Sci 39: 727–735

    Article  CAS  Google Scholar 

  • Guiney PD, Lech JJ, Peterson RE (1980) Distribution and elimination of a poly chlorinated biphenyl during early life stages of rainbow trout (Salmo gairdnerii). Toxicol Appl Pharmacol 53: 521–529

    Article  PubMed  CAS  Google Scholar 

  • Hamelink JL, Waybrant RC, Ball RC (1971) A proposal: exchange equilibria control the degree chlorinated hydrocarbons are biologically magnified in benthic environments. Trans Am Fish Soc 100: 207–214

    Article  CAS  Google Scholar 

  • Hansch C, Clayton JM (1973) Lipophilic character and biological activity of drugs II: the parabolic case. J Pharm Sci 62: 1–21

    Article  PubMed  CAS  Google Scholar 

  • Hawker DW, Connell DW (1985) Relationships between partition coefficient, uptake rate constant, clearance rate constant and time to equilibrium for bioaccumulation. Chemosphere 14:1205–1219

    Article  CAS  Google Scholar 

  • Ho NFH, Pari JY, Morozowich W, Higuchi WI (1977) The physical model approach to the design of drugs with improved intestinal absorption. In: Roche EB (ed) Design of pharmaceutical properties through prodrugs and analogs. Acad Pharm Sci, Washington DC, pp 136–227

    Google Scholar 

  • Ingebrigtsen K, Skaare JV (1983) Distribution and elimination of [14C] hexachlorobenzene after single oral exposure in the rainbow trout (Salmo gairdnerii). J Toxicol Environ Health 8: 845–856

    Article  Google Scholar 

  • Jörgensen CB (1968) Nutrition. In: Gordon MJ (Ed) Animal functions: principles and adaptations. Amarint, New Delhi, pp 12–47

    Google Scholar 

  • Kanazawa J (1981) Measurement of the bioconcentration factors of pesticides by freshwater fish and their correlation with physicochemical properties or acute toxicities. Pestic Sci 12: 417–424

    Article  CAS  Google Scholar 

  • Kenaga, EE, Goring CAI (1980) Relationship between water-solubility, soil sorption, octanolwater partitioning, and concentration of chemicals in biota. Aquat Toxicol, ASTM STP 707, Am Soc Test Mat, Philadelphia, pp 78–115

    Google Scholar 

  • Kermack DM (1955) The anatomy and physiology of the gut of the polychaete Arenicola marina (L.) Proc Zool Soc London Ser B 125: 347–381

    Google Scholar 

  • Könemann H, van Leeuwen K (1980) Toxico-kinetics in fish: accumulation and elimination of six chlorobenzenes by guppies. Chemosphere 9: 3–19

    Article  Google Scholar 

  • Koss G, Koransky W (1978) Pentachlorphenol in different species of vertebrates after administrations ofHCB and pentachlorobenzene. In: Rav R (ed) Pentachlorphenol chemistry, pharmacology and environmental toxicology. Plenum, New York London, pp 131–137

    Google Scholar 

  • Laake M (1981) Heksaklorbensen ? en ökotoxikologisk vurdering. Sjuttonde nordiska symp om vattenforskning Porsgrunn, Norway 4–7 May 1981. Nordforsk Miljövårdsser 1981:1 (in Norwegian)

    Google Scholar 

  • Laake M, Bergner P-E, Hansen N, Ingebrigtsen K, Kirkerud LA Landner L, Nyholm N, Renberg L, Riisgård HU, Skåre IUS, Svanberg O, Tarkpea M, Viktor T, Wahlgren U (1982) Bioakkumulering ved opptak fra fcpde. In: Ekotoxikologiska metoder för akvatisk miljö. Nordforsk Miljövårdsser 1982: 2 (in Norwegian) pp 96–100

    Google Scholar 

  • Landner L (1982) Systems for testing and hazard evaluation of chemicals in the aquatic environment. “ESTHER”. SNV PM 1631. Solna. 81 pp

    Google Scholar 

  • Landner L, Neilson A, Sörensen L, Tärnholm A, Viktor T (1985) Short-term test for predicting the potential of xenobiotics to impair reproductive success in fish. Ecotoxicol Environ Saf 9: 282–293

    Article  PubMed  CAS  Google Scholar 

  • Landrum PF, Scavia D (1983) Influence of sediment on anthracene uptake, depuration and biotransformation by the amphipod Hyalella azteka. Can J Fish Aquat Sci 40: 298- 305

    Article  CAS  Google Scholar 

  • Mackay D (1982) Correlation of bioconcentration factors. Environ Sci Technol 16: 274- 278

    Article  CAS  Google Scholar 

  • McKim JM, Goeden HM (1982) A direct measure of the uptake efficiency of a xenobiotic chemical across the gills of brook trout (Salvelinus fontinalis) under normoxic and hypoxic conditions. Comp Biochem Physiol 72 C: 65–74

    Google Scholar 

  • McKim J, Schneider P, Veith G (1985) Absorption dynamics of organic chemical transport across trout gills as related to octanol-water partition coefficient. Toxicol Appl Pharmacol 77:1–10

    Article  PubMed  CAS  Google Scholar 

  • Means JC, Wijayaratne R (1982) Role of natural colloids in the transport of hydrophobic pollutants. Science 215: 968–970

    Article  PubMed  CAS  Google Scholar 

  • Moriarty F (1983) Ecotoxicology. The study of pollutants in ecosystems. Academic Press, New York London

    Google Scholar 

  • Neilson A, Allard AS, Reiland S, Remberger M, Tärnholm A, Viktor T, Landner L (1984) Tri- and tetra- chloroveratrole, metabolites produced by bacterial o-methylation of tri-and tetra- chloroguiacol: An assessment of their bioconcentration potential and their effects on fish reproduction. Can J Fish Aquat Sci 41:1502–1512

    Article  CAS  Google Scholar 

  • Niimi AJ (1983) Biological and toxicological effects of environmental contaminants in fish and their eggs. Can J Fish Aquat Sci 40: 306–312

    Article  CAS  Google Scholar 

  • Niimi AJ, Cho CY (1980) Uptake of hexachlorobenzene (HCB) from feed by rainbow trout (Salmo gairdnerii.) Bull Environ Contamin Toxicol 24: 834–839

    CAS  Google Scholar 

  • Niimi AJ, Cho CY (1981) Elimination of hexachlorobenzene (HCB) by rainbow trout (Salmo gairdnerii), and an examination of its kinetics in Lake Ontario salmonids. Can J Fish Aquat Sci 38:1350–1356

    Article  CAS  Google Scholar 

  • Niimi AJ, Palazzo V (1985) Temperature effect on the elimination of pentachlorophenol, hexachlorobenzene and Mirex by rainbow trout (Salmo gairdnerii). Water Res 19: 205- 207

    Article  CAS  Google Scholar 

  • Norheim G, Roald SO (1985) Distribution and elimination of hexachlorobenzene, octachlor- ostyrene and decachlorobiphenyl in rainbow trout, Salmo gairdnerii. Aquat Toxicol 6: 13–24

    Article  CAS  Google Scholar 

  • Oliver BG, Niimi AJ (1983) Bioconcentration of chlorobenzenes from water by rainbow trout: correlation with partition coefficients and environmental residues. Environ Sci Technol 17: 287–291

    Article  CAS  Google Scholar 

  • Opperhuizen A, Jongeneel RP (1985) Mixtures of hydrophobic chemicals in aqueous environments: Aqueous solubility and bioconcentration by fish of Aroclor 1254. In: Bjørseth A, Angeletti G (eds) Organic micropollutants in the aquatic environment. Proc 4th Eur Symp, Vienna, Austria, Oct 22–24,1985

    Google Scholar 

  • Opperhuizen A, v.d. Velde EW, Gobas FAPC, Liem PAK, van der Steen JMD (1985) Relation between bioconcentration in fish and steric factors of hydrophobic chemicals. Chemosphere 14: 1871–1896

    Article  CAS  Google Scholar 

  • Opperhuizen A, Serne P, van der Steen JMD (1988) Thermodynamics of fish/water and octan-l-ol/water partitioning of some chlorinated benzenes. Environ Sci Technol 22: 286–292

    Article  CAS  Google Scholar 

  • Paasivirta J, Särkkä J, Surma-Aho K, Humppi T, Kuokkanen T, Marttinen, M (1983) Food chain enrichment of organochlorine compounds and mercury in clean and polluted lakes of Finland. Chemosphere 12 (2): 239–252

    Article  CAS  Google Scholar 

  • Pandian TJ (1975) Mechanisms of heterotrophy. In: Kinne O (ed) Marine ecology, vol 2/1.John Wiley & Sons, New York, pp 61–249

    Google Scholar 

  • Perttila M, Tervo V, Parmanne R (1982) Age dependence of the concentration of harmful substances in Baltic herring Clupea harengus. Chemosphere 11:1019–1026

    Article  CAS  Google Scholar 

  • Prosser CL (1961) Feeding and digestion. In: Prosser CL, Brown FA, Jr. (eds) Comparative animal physiology. Saunders, Philadelphia, 688 pp

    Google Scholar 

  • Rygg B, Bokn T (1976) Klorerte hydrokarboner i vann, sedimenter og organismer i Frierfjordområdet. In: Organiska miljogifter i vatten Tolfte nordiska symposiet om vattenfororening Visby, 11–13 maj 1976 (in Norwegian)

    Google Scholar 

  • Sanborn JR, Childers WF, Hansen LG (1977) Uptake and elimination of [14C] hexachlorobenzene (HCB) by the green sunfish, Lepomis cyanellus Raf, after feeding contaminated food. J Agric Food Chem 25: 551–553

    Article  PubMed  CAS  Google Scholar 

  • Schaefer RG, Ernst W, Goerke H, Eder G (1976) Residues of chlorinated hydrocarbons in North Sea animals in relation to biological parameters. Ber Dtsch Wiss Kommun Meeres- forsch 24: 225–233

    Google Scholar 

  • Schneider R (1982) Polychlorinated biphenyls (PCBs) in cod tissues from the Western Baltic: Significance of equilibrium partitioning and lipid composition in the bioaccumulation of lipophilic pollutants in gill-breathing animals. Meeresforschung 29: 69–79

    CAS  Google Scholar 

  • Schrap SM, Opperhuizen A (1985) Bioaccumulation by fish in relations hip to the oxygen concentration in water. In: Bjorseth A, Angeletti G (eds) Organic micropollutants in the aquatic environment. Proc 4th Eur Symp, Vienna, Austria, Oct 22–24,1985

    Google Scholar 

  • Schwarzenbach RP (1985) Sorption behaviour of neutral and ionizable hydrophobic organic compounds. In: Bjorseth A, Angeletti G (eds) Organic micropollutants in the aquatic environment. Proc 4th Eur Symp, Vienna, Austria, Oct 22–24,1985

    Google Scholar 

  • Stehle RG, Higuchi WI (1972) In vitro model for transport of solutes in three-phase system I Theoretical principles. J Pharm Sci 61: 1922–1930

    Article  PubMed  CAS  Google Scholar 

  • Sugiura K, Ito N, Matsumoto N, Mihara Y, Murata K, Tsukakoshi Y, Goto, M (1978) Accumulation of polychlorinated biphenyls in fish: limitation of correlation between partition coefficients and accumulation factors. Chemosphere 9: 731–736

    Article  Google Scholar 

  • Tulp MThM, Hutzinger O (1978) Some thoughts on aqueous solubilities and partition coefficients of PCB, and the mathematical correlation between bioaccumulation and physico- chemical properties. Chemosphere 10: 849–860

    Article  Google Scholar 

  • Veith GD, DeFoe DL, Bergstedt BV (1979) Measuring and estimating the bioconcentration factor of chemicals in fish. J Fish Res Bd Can 36:1040–1048

    Article  CAS  Google Scholar 

  • von Westernhagen H, Rosenthal H Dethlefsen V, Ernst W, Harns V and Hansen P-D (1981) Bioaccumulating substances and reproductive sucess in baltic flounder Platichtys flesus. Aquat Toxicol 1: 85–99

    Article  Google Scholar 

  • Weininger D (1983) Pollutant accumulation in fishes: bioenergetic constraints. 7th ASTM Symp aquatic toxicology, 17–19 April 1983

    Google Scholar 

  • Wilken RF, Wirth H (1985) The adsorption of hexachlorobenzene (HCB) in naturally occur- ing adsorbents in water. Hexachlorobenzene. Proc Int Symp. IARC Sci Publ 77. Oxford Univ Press

    Google Scholar 

  • Yalkowsky SH, Morozowich W (1980) A physical chemical basis for the design of orally active prodrugs. In: Aliens EJ (ed) Drug design. Academic Press, New York London, pp 121–185

    Google Scholar 

  • Zitko V (1974) Uptake of chlorinated paraffins and PCB from suspended solids and food by juvenile atlantic salmon. Bull Environ Contamin Toxicol 12: 406–412

    Article  CAS  Google Scholar 

  • Zitko V (1977) The accumulation of polybrominated biphenyls by fish. Bull Environ Contamin Toxicol 17: 285–292

    Article  CAS  Google Scholar 

  • Zitko V, Hutzinger O (1976) Uptake of chloro- and bromobiphenyls, hexachloro- and hexa- bromobenzene by fish. Bull Environ Contamin Toxicol 16: 665–673

    Article  CAS  Google Scholar 

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Ekelund, R. (1989). Bioaccumulation and Biomagnification of Hydrophobic Persistent Compounds as Exemplified by Hexachlorobenzene. In: Landner, L. (eds) Chemicals in the Aquatic Environment. Springer Series on Environmental Management. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61334-0_6

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  • DOI: https://doi.org/10.1007/978-3-642-61334-0_6

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