Abstract
We report here on two patients treated with Sandostatin® (octreotide) for pancreatic cholera due to metastatic VIPoma. After good initial responses, the inhibitory effect of Sandostatin (SMS) on diarrhea and VIP release disappeared and a significant rebound state developed while the treatment continued.
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References
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Koelz A., Kraenzlin M., Gyr K., Meier V., Bloom St. R., Heitz Ph., Stalder H.: Escape of the response to a long-acting somatostatin analogue (SMS 201–995) in patients with vipoma. Gastroenterology 1987, 92:527–531
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© 1989 Springer Verlag, Berlin Heidelberg
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Gyr, K., Koelz, A., Kraenzlin, M., Beglinger, C., Meier, V., Bloom, S.R. (1989). Rebound Effect and Escape of Diarrhea Inhibition Using Sandostatin® in VIPoma Patients. In: O’Dorisio, T.M. (eds) Sandostatin® in the Treatment of Gastroenteropancreatic Endocrine Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61328-9_9
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DOI: https://doi.org/10.1007/978-3-642-61328-9_9
Publisher Name: Springer, Berlin, Heidelberg
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