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The Use of Sandostatin® in Insulinomas. The Relation Between In Vivo Responses, the Presence of Somatostatin Receptors and the Development of Tachyphylaxis

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Abstract

Patients with insulin-secreting islet cell tumors are at risk for severe, protracted hypoglycemia. Surgical removal of the tumor is the treatment of choice. During the diagnostic work up, medical treatment for hypoglycemia is often mandatory, while adequate protection against hypoglycemia during operation is sometimes difficult to achieve. In cases of malignant (metastatic) insulinomas, curative surgery is, in most instances, not possible, necessitating additional (medical) therapy to protect these patients from damage caused by hypoglycemic attacks.

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© 1989 Springer Verlag, Berlin Heidelberg

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Lamberts, S.W.J., Reubi, JC. (1989). The Use of Sandostatin® in Insulinomas. The Relation Between In Vivo Responses, the Presence of Somatostatin Receptors and the Development of Tachyphylaxis. In: O’Dorisio, T.M. (eds) Sandostatin® in the Treatment of Gastroenteropancreatic Endocrine Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61328-9_5

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  • DOI: https://doi.org/10.1007/978-3-642-61328-9_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64794-9

  • Online ISBN: 978-3-642-61328-9

  • eBook Packages: Springer Book Archive

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