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Visualization and Characterization of the Scavenger Receptor in Human Liver

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Abstract

The atherogenic potential of elevated serum cholesterol levels is nowadays well established. Persons with hypercholesterolemia, usually in the form of elevated low density lipoprotein (LDL) levels, run a higher risk of developing atherosclerotic lesions than normocholesterolemic subjects of the same age. Patients with the autosomal dominant trait of familial hypercholesterolemia (FH) exhibit dramatically elevated LDL levels and are prone to massive and premature atherosclerosis. Untreated patients homozygous for FH frequently die of myocardial infarction in early childhood (Table 1).

The author is a recipient of grants from the Deutsche Forschungsgemeinschaft and from the Wissenschaftliches Herausgeberkollegium der Münchener Medizinischen Wochenschrift e. V.

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This paper is dedicated to Professor Dr. Nepomuk Zöllner on the occasion of his 65th birthday. I am grateful for his continued encouragement and support over the last 10 years.

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© 1989 Springer-Verlag Berlin Heidelberg

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Harders-Spengel, K. (1989). Visualization and Characterization of the Scavenger Receptor in Human Liver. In: Wolfram, G. (eds) Genetic and Therapeutic Aspects of Lipid and Purine Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61322-7_4

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  • DOI: https://doi.org/10.1007/978-3-642-61322-7_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50408-5

  • Online ISBN: 978-3-642-61322-7

  • eBook Packages: Springer Book Archive

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