Visualization and Characterization of the Scavenger Receptor in Human Liver

  • K. Harders-Spengel
Conference paper


The atherogenic potential of elevated serum cholesterol levels is nowadays well established. Persons with hypercholesterolemia, usually in the form of elevated low density lipoprotein (LDL) levels, run a higher risk of developing atherosclerotic lesions than normocholesterolemic subjects of the same age. Patients with the autosomal dominant trait of familial hypercholesterolemia (FH) exhibit dramatically elevated LDL levels and are prone to massive and premature atherosclerosis. Untreated patients homozygous for FH frequently die of myocardial infarction in early childhood (Table 1).


Human Liver Scavenger Receptor Familial Hypercholesterolemia Nitrocellulose Sheet Liver Membrane 
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© Springer-Verlag Berlin Heidelberg 1989

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  • K. Harders-Spengel

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