Abstract
In many patients with kidney disease, once renal excretory function is significantly compromised, filtration capacity will progressively decline until end-stage renal failure develops. In individual patients, the loss of filtration rate is linear with time and may occur despite remission of the disease process that initially damaged the kidney [59]. While progress in dialysis and transplantation has been great, therapies with prevent progressive kidney damage in humans have yet to be identified.
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Benstein, J.A., Dworkin, L.D. (1992). Glomerular Hemodynamics and Experimental Renal Injury. In: Lüscher, T.F., Kaplan, N.M. (eds) Renovascular and Renal Parenchymatous Hypertension. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61239-8_2
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DOI: https://doi.org/10.1007/978-3-642-61239-8_2
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