Abstract
The secretion and membrane insertion of proteins is a universal process occurring in living beings from bacteria to man. In prokaryotes, secretory proteins are transported directly across the plasma membrane or are inserted into it; in eukaryotes, they are initially translocated in an analogous process across the ER membrane, but are thereafter transported in vesicles to the plasma membrane. In all organisms, the translocation of proteins across and their integration into the membrane are initiated by hydrophobic signal sequences which are interchangeable; prokaryotic signal sequences can perform in eukaryotes and vice versa.
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© 1996 Springer-Verlag Berlin Heidelberg
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Rapoport, T.A. (1996). Mechanisms Involved In Co- and Posttranslational Protein Transport. In: Op den Kamp, J.A.F. (eds) Molecular Dynamics of Biomembranes. NATO ASI Series, vol 96. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61126-1_1
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DOI: https://doi.org/10.1007/978-3-642-61126-1_1
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