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Influence of c-myc on the Progression of Human Breast Cancer

  • Chapter
Attempts to Understand Metastasis Formation II

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 213/2))

Abstract

The clinical management of breast cancer patients is guided by measures of tumor growth and metastatic potential (McGuire 1987). These clinical-pathological measures involve a number of parameters including the tumor size, histological type and grade, the presence of steroid receptors, and perhaps most importantly the status of the axillary lymph nodes (Simpson and Page 1992; Fisher 1992). The scope of this assessment is, however, significantly limited in patients with node-negative tumors and those with preinvasive lesions.

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Authors and Affiliations

  1. Department of Pathology, University of Manitoba, 770 Bannatyne Avenue, R3E 0W3, Winnipeg, Manitoba, Canada

    P. H. Watson (Faculty of Medicine), R. Singh (Faculty of Medicine) & A. K. Hole (Faculty of Medicine)

  2. Department of Physiology, University of Manitoba, 770 Bannatyne Avenue, R3E 0W3, Winnipeg, Manitoba, Canada

    P. H. Watson (Faculty of Medicine)

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  1. P. H. Watson
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  2. R. Singh
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  3. A. K. Hole
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  1. Basel Institute for Immunology, Grenzacherstraße 487, CH-4005, Basel, Switzerland

    Ursula Günthert Ph.D., PD

  2. Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle-Straße 10, D-13122, Berlin, Germany

    Walter Birchmeier Ph.D.

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Watson, P.H., Singh, R., Hole, A.K. (1996). Influence of c-myc on the Progression of Human Breast Cancer. In: Günthert, U., Birchmeier, W. (eds) Attempts to Understand Metastasis Formation II. Current Topics in Microbiology and Immunology, vol 213/2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61109-4_13

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  • DOI: https://doi.org/10.1007/978-3-642-61109-4_13

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