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Toxicology - From Cells to Man pp 105–114Cite as

Connexin Genes and Cell Growth Control

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Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 18))

Abstract

In multicellular organisms, individual cells not only maintain their own functions but also must behave as members of an orderly cellular society. Thus, cell growth is controlled both at the invididual cell level as well as by homeostasis within the cellular society. Known oncogenes and tumor-suppressor genes include not only genes involved in signal transduction and the cell cycle, but also those controlling growth factors and their receptors, which are important for individual cellular functions and cell-cell interaction, respectively.

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Abbreviations

GJIC:

gap junctional intercellular communication

Cx26:

connexin 26 (similar for Cx32 and others)

SSCP:

single strand conformation polymorphism

CMTX:

X-linked Charcot-Marie-Tooth

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Author information

Authors and Affiliations

  1. Unit of Multistage Carcinogenesis, International Agency for Research on Cancer, Lyon, France

    H. Yamasaki, V. Krutovskikh, M. Mesnil & Y. Omori

Authors
  1. H. Yamasaki
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  2. V. Krutovskikh
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  3. M. Mesnil
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  4. Y. Omori
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Editor information

Editors and Affiliations

  1. Interkantonale Kontrollstelle für Heilmittel, Erlachstrasse 8, CH-3000, Bern 9, Switzerland

    Jürg P. Seiler

  2. Department of Pharmacology, Charles University of Prague, 3rd Medical School, Ruská 87, Czech Republic

    Olga Kroftová

  3. Department of Pharmacology, Charles University, Faculty of Medicine, Karlovarská 48, CZ-30166, Pilsen, Czech Republic

    Vladislav Eybl

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© 1996 Springer-Verlag Berlin Heidelberg

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Yamasaki, H., Krutovskikh, V., Mesnil, M., Omori, Y. (1996). Connexin Genes and Cell Growth Control. In: Seiler, J.P., Kroftová, O., Eybl, V. (eds) Toxicology - From Cells to Man. Archives of Toxicology, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61105-6_12

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  • DOI: https://doi.org/10.1007/978-3-642-61105-6_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64696-6

  • Online ISBN: 978-3-642-61105-6

  • eBook Packages: Springer Book Archive

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