Abstract
In multicellular organisms, individual cells not only maintain their own functions but also must behave as members of an orderly cellular society. Thus, cell growth is controlled both at the invididual cell level as well as by homeostasis within the cellular society. Known oncogenes and tumor-suppressor genes include not only genes involved in signal transduction and the cell cycle, but also those controlling growth factors and their receptors, which are important for individual cellular functions and cell-cell interaction, respectively.
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Abbreviations
- GJIC:
-
gap junctional intercellular communication
- Cx26:
-
connexin 26 (similar for Cx32 and others)
- SSCP:
-
single strand conformation polymorphism
- CMTX:
-
X-linked Charcot-Marie-Tooth
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© 1996 Springer-Verlag Berlin Heidelberg
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Yamasaki, H., Krutovskikh, V., Mesnil, M., Omori, Y. (1996). Connexin Genes and Cell Growth Control. In: Seiler, J.P., Kroftová, O., Eybl, V. (eds) Toxicology - From Cells to Man. Archives of Toxicology, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61105-6_12
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DOI: https://doi.org/10.1007/978-3-642-61105-6_12
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