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Bleomycin-Induced Injury, Mouse. A Model for Lung Injury

  • Chapter
Respiratory System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

The gross appearance does not distinguish developing and established fibrotic lesions induced by bleomycin from injury caused by drugs or other chemicals. After a single intravenous dose fibrosis is multifocal, rarely confluent; diffuse lobular and lobar fibrosis follow endotracheal administration.

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Authors
  1. Drummond H. Bowden
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Editors and Affiliations

  1. ILSI Research Foundation, Harvard Medical School, 1126 Sixteenth Street,N.W., Washington, DC, 20036, USA

    Thomas Caryle Jones D.V.M., D.Sc. (Professor of Comparative Pathology Emeritus) (Professor of Comparative Pathology Emeritus)

  2. University of California, Davis, 6260 Cape George Road, Port Townsend, WA, 98368, USA

    Donald L. Dungworth B.V.Sc, Ph.D., M.R.C.V.S. (Professor of Veterinary Pathology, Emeritus) (Professor of Veterinary Pathology, Emeritus)

  3. Medizinische Hochschule Hannover, Institut für Experimentelle Pathologie, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Germany

    Ulrich Mohr MD (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1996 Springer-Verlag Berlin Heidelberg

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Bowden, D.H. (1996). Bleomycin-Induced Injury, Mouse. A Model for Lung Injury. In: Jones, T.C., Dungworth, D.L., Mohr, U. (eds) Respiratory System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61042-4_25

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  • DOI: https://doi.org/10.1007/978-3-642-61042-4_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64667-6

  • Online ISBN: 978-3-642-61042-4

  • eBook Packages: Springer Book Archive

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