Thyroid Gland, Gravidity and Puerperium

  • H. G. Bohnet
Conference paper


This chapter aims at elucidating some special aspects of thyroidal disturbances and diseases. Hormonal and metabolic alterations during pregnancy exert complex influences on thyroidal function. The primary cause is an estrogen-induced surplus synthesis of thyroxine-binding globulin (TBG) in the liver, producing significantly higher serum levels of total T3 and T4. As a consequence, it is far more difficult to diagnose disturbances of thyroidal function during pregnancy and childbed when TBG decline occurs. Treatment is extremely difficult due to permeability of the placenta by certain medications or substances (e.g., thyreostatics, iodine) as opposed to others (thyroxine).


Thyroid Gland Iodine Supply Additional Iodine Postpartum Thyroid Dysfunction Hypothyroid Mother 
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© Springer-Verlag Berlin Heidelberg 1996

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  • H. G. Bohnet

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